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olfactory receptor 601 [Mus musculus]

NCBI Reference Sequence: NP_666426.2

Identical Proteins FASTA Graphics 

LOCUS       NP_666426                314 aa            linear   ROD 24-OCT-2024
DEFINITION  olfactory receptor 601 [Mus musculus].
ACCESSION   NP_666426
VERSION     NP_666426.2
DBSOURCE    REFSEQ: accession NM_146314.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 314)
  AUTHORS   L,G.B., Jg,H., I,L.T., M,J.M. and P,B.A.
  TITLE     The Sperm Olfactory Receptor OLFR601 is Dispensable for Mouse
            Fertilization
  JOURNAL   Front Cell Dev Biol 10, 854115 (2022)
   PUBMED   35721474
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 314)
  AUTHORS   Olender,T., Jones,T.E.M., Bruford,E. and Lancet,D.
  TITLE     A unified nomenclature for vertebrate olfactory receptors
  JOURNAL   BMC Evol Biol 20 (1), 42 (2020)
   PUBMED   32295537
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 314)
  AUTHORS   Young,J.M., Shykind,B.M., Lane,R.P., Tonnes-Priddy,L., Ross,J.A.,
            Walker,M., Williams,E.M. and Trask,B.J.
  TITLE     Odorant receptor expressed sequence tags demonstrate olfactory
            expression of over 400 genes, extensive alternate splicing and
            unequal expression levels
  JOURNAL   Genome Biol 4 (11), R71 (2003)
   PUBMED   14611657
REFERENCE   4  (residues 1 to 314)
  AUTHORS   Young,J.M., Friedman,C., Williams,E.M., Ross,J.A., Tonnes-Priddy,L.
            and Trask,B.J.
  TITLE     Different evolutionary processes shaped the mouse and human
            olfactory receptor gene families
  JOURNAL   Hum Mol Genet 11 (5), 535-546 (2002)
   PUBMED   11875048
  REMARK    Erratum:[Hum Mol Genet. 2002 Jul 1;11(14):1683.]
REFERENCE   5  (residues 1 to 314)
  AUTHORS   Zhang,X. and Firestein,S.
  TITLE     The olfactory receptor gene superfamily of the mouse
  JOURNAL   Nat Neurosci 5 (2), 124-133 (2002)
   PUBMED   11802173
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC108410.9.
            
            On Nov 18, 2009 this sequence version replaced NP_666426.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC131956.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..314
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 54.85 cM"
     Protein         1..314
                     /product="olfactory receptor 601"
                     /note="olfactory receptor MOR24-3;
                     GA_x6K02T2PBJ9-6068534-6067590"
                     /calculated_mol_wt=34839
     Region          27..301
                     /region_name="7tmA_OR52R_52L-like"
                     /note="olfactory receptor subfamily 52R, 52L, and related
                     proteins, member of the class A family of
                     seven-transmembrane G protein-coupled receptors; cd15951"
                     /db_xref="CDD:320617"
     Region          28..54
                     /region_name="TM helix 1"
                     /note="TM helix 1 [structural motif]"
                     /db_xref="CDD:320617"
     Region          61..87
                     /region_name="TM helix 2"
                     /note="TM helix 2 [structural motif]"
                     /db_xref="CDD:320617"
     Site            order(83,86..87,99..104,106..107,110,155,157..161,197,
                     200..202,204..206,208..209,254,257..258,260..261,264,
                     272..273,275..277,280,283..284)
                     /site_type="other"
                     /note="putative ligand binding pocket [chemical binding]"
                     /db_xref="CDD:320617"
     Region          99..129
                     /region_name="TM helix 3"
                     /note="TM helix 3 [structural motif]"
                     /db_xref="CDD:320617"
     Region          142..163
                     /region_name="TM helix 4"
                     /note="TM helix 4 [structural motif]"
                     /db_xref="CDD:320617"
     Region          197..227
                     /region_name="TM helix 5"
                     /note="TM helix 5 [structural motif]"
                     /db_xref="CDD:320617"
     Region          234..264
                     /region_name="TM helix 6"
                     /note="TM helix 6 [structural motif]"
                     /db_xref="CDD:320617"
     Region          273..298
                     /region_name="TM helix 7"
                     /note="TM helix 7 [structural motif]"
                     /db_xref="CDD:320617"
     CDS             1..314
                     /gene="Or52s19"
                     /gene_synonym="MOR24-3; Olfr601"
                     /coded_by="NM_146314.2:22..966"
                     /db_xref="CCDS:CCDS21570.1"
                     /db_xref="GeneID:258311"
                     /db_xref="MGI:MGI:3030435"
ORIGIN      
        1 mgpanksqls pstfwlmgip glehlhvwig ipfcsmymva lmgnvtilav vraertlhep
       61 mflflcmlsv tdlvlststl prmlclfwma ahditfdacl aqmffihsft amesgfflam
      121 aidryvaicd plrhatilth sriavmgavv vlrgvgffsp hpvllkqlpy crtriiahty
      181 cefmavvkla cleigatkry slgvafgigs cdcffiaisy vlilravfrl psreaslkal
      241 gtcgshvcvi vvfystagft flthrfghnv aprthilian myllvppfln pivygvrtkk
      301 irdyvlntlk vkgs
//
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Reference sequence information

  • RefSeq mRNA
    See reference mRNA sequence for the Or52s19 gene (NM_146314.2).

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