LOCUS NP_666426 314 aa linear ROD 24-OCT-2024
DEFINITION olfactory receptor 601 [Mus musculus].
ACCESSION NP_666426
VERSION NP_666426.2
DBSOURCE REFSEQ: accession NM_146314.2
KEYWORDS RefSeq; RefSeq Select.
SOURCE Mus musculus (house mouse)
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE 1 (residues 1 to 314)
AUTHORS L,G.B., Jg,H., I,L.T., M,J.M. and P,B.A.
TITLE The Sperm Olfactory Receptor OLFR601 is Dispensable for Mouse
Fertilization
JOURNAL Front Cell Dev Biol 10, 854115 (2022)
PUBMED 35721474
REMARK Publication Status: Online-Only
REFERENCE 2 (residues 1 to 314)
AUTHORS Olender,T., Jones,T.E.M., Bruford,E. and Lancet,D.
TITLE A unified nomenclature for vertebrate olfactory receptors
JOURNAL BMC Evol Biol 20 (1), 42 (2020)
PUBMED 32295537
REMARK Publication Status: Online-Only
REFERENCE 3 (residues 1 to 314)
AUTHORS Young,J.M., Shykind,B.M., Lane,R.P., Tonnes-Priddy,L., Ross,J.A.,
Walker,M., Williams,E.M. and Trask,B.J.
TITLE Odorant receptor expressed sequence tags demonstrate olfactory
expression of over 400 genes, extensive alternate splicing and
unequal expression levels
JOURNAL Genome Biol 4 (11), R71 (2003)
PUBMED 14611657
REFERENCE 4 (residues 1 to 314)
AUTHORS Young,J.M., Friedman,C., Williams,E.M., Ross,J.A., Tonnes-Priddy,L.
and Trask,B.J.
TITLE Different evolutionary processes shaped the mouse and human
olfactory receptor gene families
JOURNAL Hum Mol Genet 11 (5), 535-546 (2002)
PUBMED 11875048
REMARK Erratum:[Hum Mol Genet. 2002 Jul 1;11(14):1683.]
REFERENCE 5 (residues 1 to 314)
AUTHORS Zhang,X. and Firestein,S.
TITLE The olfactory receptor gene superfamily of the mouse
JOURNAL Nat Neurosci 5 (2), 124-133 (2002)
PUBMED 11802173
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
AC108410.9.
On Nov 18, 2009 this sequence version replaced NP_666426.1.
Summary: Olfactory receptors interact with odorant molecules in the
nose, to initiate a neuronal response that triggers the perception
of a smell. The olfactory receptor proteins are members of a large
family of G-protein-coupled receptors (GPCR) arising from single
coding-exon genes. Olfactory receptors share a 7-transmembrane
domain structure with many neurotransmitter and hormone receptors
and are responsible for the recognition and G protein-mediated
transduction of odorant signals. The olfactory receptor gene family
is the largest in the genome. [provided by RefSeq, Jul 2008].
Sequence Note: The RefSeq transcript and protein were derived from
genomic sequence to make the sequence consistent with the reference
genome assembly. The genomic coordinates used for the transcript
record were based on alignments.
##Evidence-Data-START##
Transcript is intronless :: BC131956.1 [ECO:0000345]
##Evidence-Data-END##
##RefSeq-Attributes-START##
RefSeq Select criteria :: based on single protein-coding transcript
##RefSeq-Attributes-END##
FEATURES Location/Qualifiers
source 1..314
/organism="Mus musculus"
/strain="C57BL/6"
/db_xref="taxon:10090"
/chromosome="7"
/map="7 54.85 cM"
Protein 1..314
/product="olfactory receptor 601"
/note="olfactory receptor MOR24-3;
GA_x6K02T2PBJ9-6068534-6067590"
/calculated_mol_wt=34839
Region 27..301
/region_name="7tmA_OR52R_52L-like"
/note="olfactory receptor subfamily 52R, 52L, and related
proteins, member of the class A family of
seven-transmembrane G protein-coupled receptors; cd15951"
/db_xref="CDD:320617"
Region 28..54
/region_name="TM helix 1"
/note="TM helix 1 [structural motif]"
/db_xref="CDD:320617"
Region 61..87
/region_name="TM helix 2"
/note="TM helix 2 [structural motif]"
/db_xref="CDD:320617"
Site order(83,86..87,99..104,106..107,110,155,157..161,197,
200..202,204..206,208..209,254,257..258,260..261,264,
272..273,275..277,280,283..284)
/site_type="other"
/note="putative ligand binding pocket [chemical binding]"
/db_xref="CDD:320617"
Region 99..129
/region_name="TM helix 3"
/note="TM helix 3 [structural motif]"
/db_xref="CDD:320617"
Region 142..163
/region_name="TM helix 4"
/note="TM helix 4 [structural motif]"
/db_xref="CDD:320617"
Region 197..227
/region_name="TM helix 5"
/note="TM helix 5 [structural motif]"
/db_xref="CDD:320617"
Region 234..264
/region_name="TM helix 6"
/note="TM helix 6 [structural motif]"
/db_xref="CDD:320617"
Region 273..298
/region_name="TM helix 7"
/note="TM helix 7 [structural motif]"
/db_xref="CDD:320617"
CDS 1..314
/gene="Or52s19"
/gene_synonym="MOR24-3; Olfr601"
/coded_by="NM_146314.2:22..966"
/db_xref="CCDS:CCDS21570.1"
/db_xref="GeneID:258311"
/db_xref="MGI:MGI:3030435"
ORIGIN
1 mgpanksqls pstfwlmgip glehlhvwig ipfcsmymva lmgnvtilav vraertlhep
61 mflflcmlsv tdlvlststl prmlclfwma ahditfdacl aqmffihsft amesgfflam
121 aidryvaicd plrhatilth sriavmgavv vlrgvgffsp hpvllkqlpy crtriiahty
181 cefmavvkla cleigatkry slgvafgigs cdcffiaisy vlilravfrl psreaslkal
241 gtcgshvcvi vvfystagft flthrfghnv aprthilian myllvppfln pivygvrtkk
301 irdyvlntlk vkgs
//