LOCUS NP_001000493 312 aa linear ROD 26-OCT-2024
DEFINITION olfactory receptor Olr1356 [Rattus norvegicus].
ACCESSION NP_001000493 XP_220215
VERSION NP_001000493.1
DBSOURCE REFSEQ: accession NM_001000493.1
KEYWORDS RefSeq; RefSeq Select.
SOURCE Rattus norvegicus (Norway rat)
ORGANISM Rattus norvegicus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Rattus.
REFERENCE 1 (residues 1 to 312)
AUTHORS Zhang,R., Pan,Y., Ahmed,L., Block,E., Zhang,Y., Batista,V.S. and
Zhuang,H.
TITLE A Multispecific Investigation of the Metal Effect in Mammalian
Odorant Receptors for Sulfur-Containing Compounds
JOURNAL Chem Senses 43 (5), 357-366 (2018)
PUBMED 29659735
REFERENCE 2 (residues 1 to 312)
AUTHORS Block,E., Jang,S., Matsunami,H., Sekharan,S., Dethier,B.,
Ertem,M.Z., Gundala,S., Pan,Y., Li,S., Li,Z., Lodge,S.N., Ozbil,M.,
Jiang,H., Penalba,S.F., Batista,V.S. and Zhuang,H.
TITLE Implausibility of the vibrational theory of olfaction
JOURNAL Proc Natl Acad Sci U S A 112 (21), E2766-E2774 (2015)
PUBMED 25901328
REFERENCE 3 (residues 1 to 312)
AUTHORS Fleischer,J., Schwarzenbacher,K., Besser,S., Hass,N. and Breer,H.
TITLE Olfactory receptors and signalling elements in the Grueneberg
ganglion
JOURNAL J Neurochem 98 (2), 543-554 (2006)
PUBMED 16805845
REFERENCE 4 (residues 1 to 312)
AUTHORS Vanderhaeghen,P., Schurmans,S., Vassart,G. and Parmentier,M.
TITLE Specific repertoire of olfactory receptor genes in the male germ
cells of several mammalian species
JOURNAL Genomics 39 (3), 239-246 (1997)
PUBMED 9119360
COMMENT REVIEWED REFSEQ: This record has been curated by Janet Young and
Barbara Trask (FHCRC). The reference sequence was derived from
JAXUCZ010000010.1.
On Aug 30, 2004 this sequence version replaced XP_220215.1.
Summary: Olfactory receptors interact with odorant molecules in the
nose, to initiate a neuronal response that triggers the perception
of a smell. The olfactory receptor proteins are members of a large
family of G-protein-coupled receptors (GPCR) arising from single
coding-exon genes. Olfactory receptors share a 7-transmembrane
domain structure with many neurotransmitter and hormone receptors
and are responsible for the recognition and G protein-mediated
transduction of odorant signals. The olfactory receptor gene family
is the largest in the genome. [provided by RefSeq, Jul 2008].
Sequence Note: The RefSeq transcript and protein were derived from
genomic sequence to make the sequence consistent with the reference
genome assembly. The genomic coordinates used for the transcript
record were based on alignments.
##RefSeq-Attributes-START##
RefSeq Select criteria :: based on single protein-coding transcript
##RefSeq-Attributes-END##
FEATURES Location/Qualifiers
source 1..312
/organism="Rattus norvegicus"
/strain="BN"
/db_xref="taxon:10116"
/chromosome="10"
/map="10q12"
Protein 1..312
/product="olfactory receptor Olr1356"
/note="olfactory receptor 1356; olfactory receptor gene
Olr1356"
/calculated_mol_wt=34275
Region 25..294
/region_name="7tmA_OR2B-like"
/note="olfactory receptor subfamily 2B and related
proteins, member of the class A family of
seven-transmembrane G protein-coupled receptors; cd15947"
/db_xref="CDD:320613"
Region 26..52
/region_name="TM helix 1"
/note="TM helix 1 [structural motif]"
/db_xref="CDD:320613"
Region 59..85
/region_name="TM helix 2"
/note="TM helix 2 [structural motif]"
/db_xref="CDD:320613"
Site order(81,84..85,97..102,104..105,108,153,155..159,195,
198..200,202..204,206..207,252,255..256,258..259,262,
268..269,271..273,276,279..280)
/site_type="other"
/note="putative ligand binding pocket [chemical binding]"
/db_xref="CDD:320613"
Region 97..127
/region_name="TM helix 3"
/note="TM helix 3 [structural motif]"
/db_xref="CDD:320613"
Region 140..161
/region_name="TM helix 4"
/note="TM helix 4 [structural motif]"
/db_xref="CDD:320613"
Region 195..225
/region_name="TM helix 5"
/note="TM helix 5 [structural motif]"
/db_xref="CDD:320613"
Region 232..262
/region_name="TM helix 6"
/note="TM helix 6 [structural motif]"
/db_xref="CDD:320613"
Region 269..294
/region_name="TM helix 7"
/note="TM helix 7 [structural motif]"
/db_xref="CDD:320613"
CDS 1..312
/gene="Or2c1"
/gene_synonym="Olr1356"
/coded_by="NM_001000493.1:1..939"
/db_xref="GeneID:302954"
/db_xref="RGD:1334376"
ORIGIN
1 mevgsnissg sfilmgisnh pqleiiffvv ilssylltlv gnltiillsr ldarlhtpmy
61 fflsnlssld lafttssvpq mlknlwgpdk tisyggcvtq lyvflwlgat ecillvvmaf
121 dryvavcrpl hymtvmnprl cwvlaaiswl gglgnsviqs tftlqlpfcg hrkvdnflce
181 vpamiklacg dtslneavln gvctfftavp lsiilvsycf iaqavmkirs vegrrkafnt
241 cvshlvvvfl fygsaiygyl lpakssnqdq gkfislfysv vtpmvnpliy tlrnkevkga
301 lgrllgkgrg as
//