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olfactory receptor Olr1356 [Rattus norvegicus]

NCBI Reference Sequence: NP_001000493.1

Identical Proteins FASTA Graphics 

LOCUS       NP_001000493             312 aa            linear   ROD 26-OCT-2024
DEFINITION  olfactory receptor Olr1356 [Rattus norvegicus].
ACCESSION   NP_001000493 XP_220215
VERSION     NP_001000493.1
DBSOURCE    REFSEQ: accession NM_001000493.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 312)
  AUTHORS   Zhang,R., Pan,Y., Ahmed,L., Block,E., Zhang,Y., Batista,V.S. and
            Zhuang,H.
  TITLE     A Multispecific Investigation of the Metal Effect in Mammalian
            Odorant Receptors for Sulfur-Containing Compounds
  JOURNAL   Chem Senses 43 (5), 357-366 (2018)
   PUBMED   29659735
REFERENCE   2  (residues 1 to 312)
  AUTHORS   Block,E., Jang,S., Matsunami,H., Sekharan,S., Dethier,B.,
            Ertem,M.Z., Gundala,S., Pan,Y., Li,S., Li,Z., Lodge,S.N., Ozbil,M.,
            Jiang,H., Penalba,S.F., Batista,V.S. and Zhuang,H.
  TITLE     Implausibility of the vibrational theory of olfaction
  JOURNAL   Proc Natl Acad Sci U S A 112 (21), E2766-E2774 (2015)
   PUBMED   25901328
REFERENCE   3  (residues 1 to 312)
  AUTHORS   Fleischer,J., Schwarzenbacher,K., Besser,S., Hass,N. and Breer,H.
  TITLE     Olfactory receptors and signalling elements in the Grueneberg
            ganglion
  JOURNAL   J Neurochem 98 (2), 543-554 (2006)
   PUBMED   16805845
REFERENCE   4  (residues 1 to 312)
  AUTHORS   Vanderhaeghen,P., Schurmans,S., Vassart,G. and Parmentier,M.
  TITLE     Specific repertoire of olfactory receptor genes in the male germ
            cells of several mammalian species
  JOURNAL   Genomics 39 (3), 239-246 (1997)
   PUBMED   9119360
COMMENT     REVIEWED REFSEQ: This record has been curated by Janet Young and
            Barbara Trask (FHCRC). The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Aug 30, 2004 this sequence version replaced XP_220215.1.
            
            Summary: Olfactory receptors interact with odorant molecules in the
            nose, to initiate a neuronal response that triggers the perception
            of a smell. The olfactory receptor proteins are members of a large
            family of G-protein-coupled receptors (GPCR) arising from single
            coding-exon genes. Olfactory receptors share a 7-transmembrane
            domain structure with many neurotransmitter and hormone receptors
            and are responsible for the recognition and G protein-mediated
            transduction of odorant signals. The olfactory receptor gene family
            is the largest in the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q12"
     Protein         1..312
                     /product="olfactory receptor Olr1356"
                     /note="olfactory receptor 1356; olfactory receptor gene
                     Olr1356"
                     /calculated_mol_wt=34275
     Region          25..294
                     /region_name="7tmA_OR2B-like"
                     /note="olfactory receptor subfamily 2B and related
                     proteins, member of the class A family of
                     seven-transmembrane G protein-coupled receptors; cd15947"
                     /db_xref="CDD:320613"
     Region          26..52
                     /region_name="TM helix 1"
                     /note="TM helix 1 [structural motif]"
                     /db_xref="CDD:320613"
     Region          59..85
                     /region_name="TM helix 2"
                     /note="TM helix 2 [structural motif]"
                     /db_xref="CDD:320613"
     Site            order(81,84..85,97..102,104..105,108,153,155..159,195,
                     198..200,202..204,206..207,252,255..256,258..259,262,
                     268..269,271..273,276,279..280)
                     /site_type="other"
                     /note="putative ligand binding pocket [chemical binding]"
                     /db_xref="CDD:320613"
     Region          97..127
                     /region_name="TM helix 3"
                     /note="TM helix 3 [structural motif]"
                     /db_xref="CDD:320613"
     Region          140..161
                     /region_name="TM helix 4"
                     /note="TM helix 4 [structural motif]"
                     /db_xref="CDD:320613"
     Region          195..225
                     /region_name="TM helix 5"
                     /note="TM helix 5 [structural motif]"
                     /db_xref="CDD:320613"
     Region          232..262
                     /region_name="TM helix 6"
                     /note="TM helix 6 [structural motif]"
                     /db_xref="CDD:320613"
     Region          269..294
                     /region_name="TM helix 7"
                     /note="TM helix 7 [structural motif]"
                     /db_xref="CDD:320613"
     CDS             1..312
                     /gene="Or2c1"
                     /gene_synonym="Olr1356"
                     /coded_by="NM_001000493.1:1..939"
                     /db_xref="GeneID:302954"
                     /db_xref="RGD:1334376"
ORIGIN      
        1 mevgsnissg sfilmgisnh pqleiiffvv ilssylltlv gnltiillsr ldarlhtpmy
       61 fflsnlssld lafttssvpq mlknlwgpdk tisyggcvtq lyvflwlgat ecillvvmaf
      121 dryvavcrpl hymtvmnprl cwvlaaiswl gglgnsviqs tftlqlpfcg hrkvdnflce
      181 vpamiklacg dtslneavln gvctfftavp lsiilvsycf iaqavmkirs vegrrkafnt
      241 cvshlvvvfl fygsaiygyl lpakssnqdq gkfislfysv vtpmvnpliy tlrnkevkga
      301 lgrllgkgrg as
//
Feature
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