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Beta-hexosaminidase A [Caenorhabditis elegans]

NCBI Reference Sequence: NP_508409.1

Identical Proteins FASTA Graphics 

LOCUS       NP_508409                555 aa            linear   INV 04-DEC-2024
DEFINITION  Beta-hexosaminidase A [Caenorhabditis elegans].
ACCESSION   NP_508409
VERSION     NP_508409.1
DBLINK      BioProject: PRJNA158
DBSOURCE    REFSEQ: accession NM_076008.8
KEYWORDS    RefSeq.
SOURCE      Caenorhabditis elegans
  ORGANISM  Caenorhabditis elegans
            Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
            Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
            Caenorhabditis.
REFERENCE   1  (residues 1 to 555)
  AUTHORS   Sulson,J.E. and Waterston,R.
  CONSRTM   Caenorhabditis elegans Sequencing Consortium
  TITLE     Genome sequence of the nematode C. elegans: a platform for
            investigating biology
  JOURNAL   Science 282 (5396), 2012-2018 (1998)
   PUBMED   9851916
  REMARK    Erratum:[Science 1999 Jan 1;283(5398):35]
REFERENCE   2  (residues 1 to 555)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-DEC-2024) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 555)
  AUTHORS   WormBase.
  CONSRTM   WormBase Consortium
  TITLE     Direct Submission
  JOURNAL   Submitted (17-OCT-2024) WormBase Group, European Bioinformatics
            Institute, Cambridge, CB10 1SA, UK. Email: help@wormbase.org
REFERENCE   4  (residues 1 to 555)
  AUTHORS   Sulson,J.E. and Waterston,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-MAR-2003) Nematode Sequencing Project: Sanger
            Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome Institute
            at Washington University, St. Louis, MO 63110, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by WormBase. The
            reference sequence is identical to CCD68941.
FEATURES             Location/Qualifiers
     source          1..555
                     /organism="Caenorhabditis elegans"
                     /strain="Bristol N2"
                     /db_xref="taxon:6239"
                     /chromosome="X"
     Protein         1..555
                     /product="Beta-hexosaminidase A"
                     /calculated_mol_wt=64248
     Region          34..147
                     /region_name="Glyco_hydro_20b"
                     /note="Glycosyl hydrolase family 20, domain 2; cl03741"
                     /db_xref="CDD:446174"
     Region          170..529
                     /region_name="GH20_HexA_HexB-like"
                     /note="Beta-N-acetylhexosaminidases catalyze the removal
                     of beta-1,4-linked N-acetyl-D-hexosamine residues from the
                     non-reducing ends of N-acetyl-beta-D-hexosaminides
                     including N-acetylglucosides and N-acetylgalactosides. The
                     hexA and hexB genes encode the...; cd06562"
                     /db_xref="CDD:119332"
     Site            order(181,210,264,324..325,380,398,427,429,477,479)
                     /site_type="active"
                     /db_xref="CDD:119332"
     CDS             1..555
                     /gene="hex-1"
                     /locus_tag="CELE_T14F9.3"
                     /standard_name="T14F9.3"
                     /coded_by="NM_076008.8:4..1671"
                     /note="Confirmed by transcript evidence"
                     /db_xref="GeneID:180533"
                     /db_xref="WormBase:WBGene00020509"
ORIGIN      
        1 mrllipilif alittavtwf ygrddpdrws vggvwplpkk ivygsknrti tydkigidlg
       61 dkkdcdills madnymnkwl fpfpvemktg gtedfiitvt vkdecpsgpp vhgaseeyll
      121 rvslteavin aqtvwgalra meslshlvfy dhksqeyqir tveifdkprf pvrgimidss
      181 rhflsvnvik rqleimsmnk lnvlhwhlvd sesfpytsvk fpelhgvgay sprhvysred
      241 iadviafarl rgirvipefd lpghtsswrg rkgfltecfd ekgvetflpn lvdpmneanf
      301 dfisefleev tetfpdqflh lggdevsdyi vecwernkki rkfmeekgfg ndtvllenyf
      361 feklykiven lklkrkpifw qevfdnnipd pnavihiwkg ntheeiyeqv knitsqnfpv
      421 ivsacwylny ikygadwrde irgtapsnsr yyycdptnfn gtvaqkelvw ggiaaiwgel
      481 vdntniearl wprasaaaer lwspaektqr aedawprmhe lrcrlvsrgy riqpnnnpdy
      541 cpfefdeppa tktel
//
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Reference sequence information

  • RefSeq mRNA
    See reference mRNA sequence for the hex-1 gene (NM_076008.8).

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