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NCBI Reference Sequence: XP_021328563.1
Identical Proteins FASTA Graphics
LOCUS XP_021328563 2420 aa linear VRT 08-SEP-2024 DEFINITION CREB binding protein b isoform X1 [Danio rerio]. ACCESSION XP_021328563 VERSION XP_021328563.1 DBLINK BioProject: PRJNA13922 DBSOURCE REFSEQ: accession XM_021472888.2 KEYWORDS RefSeq. SOURCE Danio rerio (zebrafish) ORGANISM Danio rerio Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007114.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_000002035.6-RS_2024_08 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 08/15/2024 ##Genome-Annotation-Data-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..2420 /organism="Danio rerio" /strain="Tuebingen" /db_xref="taxon:7955" /chromosome="3" Protein 1..2420 /product="CREB binding protein b isoform X1" /calculated_mol_wt=266087 Region 338..405 /region_name="zf-TAZ" /note="TAZ zinc finger; pfam02135" /db_xref="CDD:460457" Region 550..630 /region_name="KIX" /note="KIX domain; pfam02172" /db_xref="CDD:366953" Region 637..>906 /region_name="Med15" /note="ARC105 or Med15 subunit of Mediator complex non-fungal; pfam09606" /db_xref="CDD:312941" Region <857..>980 /region_name="PspC_subgroup_2" /note="pneumococcal surface protein PspC, LPXTG-anchored form; NF033839" /db_xref="CDD:468202" Region 1021..1128 /region_name="Bromo_cbp_like" /note="Bromodomain, cbp_like subfamily. Cbp (CREB binding protein or CREBBP) is an acetyltransferase acting on histone, which gives a specific tag for transcriptional activation and also acetylates non-histone proteins. CREBBP binds specifically to...; cd05495" /db_xref="CDD:99927" Site order(1049,1056,1059,1098,1102,1108) /site_type="active" /note="acetyllysine binding site [active]" /db_xref="CDD:99927" Region 1140..1212 /region_name="RING_CBP-p300" /note="atypical RING domain found in CREB-binding protein and p300 histone acetyltransferases; cd15802" /db_xref="CDD:276805" Site order(1140,1143..1144,1210,1212) /site_type="other" /note="HAT interface [polypeptide binding]" /db_xref="CDD:276805" Region 1213..1247 /region_name="PHD_CBP" /note="PHD finger found in CREB-binding protein (CBP); cd15647" /db_xref="CDD:277117" Site order(1213..1217,1221,1240) /site_type="other" /note="putative histone H3 binding site [polypeptide binding]" /db_xref="CDD:277117" Region 1276..1583 /region_name="HAT_KAT11" /note="Histone acetylation protein; pfam08214" /db_xref="CDD:400497" Region 1639..1679 /region_name="ZZ_CBP" /note="Zinc finger, ZZ type. Zinc finger present in CBP/p300 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. CREB-binding protein (CBP) is a large multidomain protein that...; cd02337" /db_xref="CDD:239077" Site order(1641,1644,1654,1657,1663,1666,1672,1674) /site_type="other" /note="Zinc-binding sites [ion binding]" /db_xref="CDD:239077" Site order(1641,1644,1663,1666) /site_type="other" /note="zinc cluster 1 [ion binding]" /db_xref="CDD:239077" Site order(1642,1651,1653,1659,1661) /site_type="active" /note="putative charged binding surface [active]" /db_xref="CDD:239077" Site order(1652,1667,1676,1679) /site_type="active" /note="putative hydrophobic binding surface [active]" /db_xref="CDD:239077" Site order(1654,1657,1672,1674) /site_type="other" /note="zinc cluster 2 [ion binding]" /db_xref="CDD:239077" Region 1706..1774 /region_name="zf-TAZ" /note="TAZ zinc finger; pfam02135" /db_xref="CDD:460457" Region 2013..2114 /region_name="Creb_binding" /note="Creb binding; pfam09030" /db_xref="CDD:462659" CDS 1..2420 /gene="crebbpb" /gene_synonym="CBP-A; gb:dq017638; im:7150488; si:ch211-121i18.1; wu:fp53a03; Zfcbp" /coded_by="XM_021472888.2:739..8001" /db_xref="GeneID:567111" /db_xref="ZFIN:ZDB-GENE-050302-102" ORIGIN 1 madnlldmgp saakrpklns palsssdtpd fvslfdlend lpdelipngd lglmsmpsng 61 dggvgsrmgg nvpdaaakhk qlsqllqags gsglggnlsp qsgmggqlga lgkspmgqgs 121 pghqtqapkp vgtptgqgnn spgmgmntgf npamlnnnnq ahglmgqnmt pqgqmmngvm 181 gpagrgrtap gmqyqgqgmq gapvgagggq gvgvsgsvla etltqgapqm gahnainqqa 241 gnmnkmglat angpfgqqyv qgsvqqmsna glnaqmqnka alpnslqptl kgassvpnll 301 qqqvpsvgmv pgqgvsagpt adpekrkliq qqlvlllhah kcqrreqang evracalphc 361 rtmknvlnhm thcqagkscq vahcassrqi ishwknctrh dcpvclplkn asdkrnqqpm 421 lsspnpgmqs plgqvgtsqp aapaissgth idpssmqray aalglpygnq paaqtqvagq 481 qptqtqqmrs maalgsnqmn iggngmadqt nlhtdsslps slssnqmmpd gsnmggagnl 541 ptaaplsmpg mkkpwhehvt qdlrnhlvhk lvqaifptpd paalkdrrme nlvayarkve 601 gdmyesansr deyyhflaek iykiqkelee krksrlskpq mgaqgpqqpg lpqpnpmgpa 661 qairppngpv smsnvpnqlm armqvpqgmg qfnpvtmqnv qmsqsqvgap raaspmthnp 721 qmgmgnvppm vmspsrmpqa qammgghann mvgqtpnqnq fmnqtpfpas aggmnvnvnl 781 aqqsgqtvqq qqqqnanltl navgslgpps alcstpppps astpsaaasl qslqtqpstp 841 asvgghvtpt hipsglprpp svlgsspaps qphtplqsqp eppmqmqqpt svqaqqpstp 901 lsqmapsvdn rvptpasvae thsqqalpdy paaepkiehq edeqevesgk krpdikmede 961 dvkppqvkeq petvepkqep metedkkpet ktepkeeevs stnsstpanq saqsrkkifk 1021 peelrqalmp tlealyrqdp eslpfrqpvd pnllgipdyf divknpidls tikrkldtgq 1081 yqepwqyvdd iwlmfnnawl ynrktsrvyk ycsklaevfe qeidpvmqgl gyccgrkyef 1141 spqtlccygk qlctisrdgt yysyqnryhf cekcfneiqg dsvtlgddpt qsqtmiskeq 1201 fekkkndtld sepfveckdc grkmhqicvl hydviwpsgf icdnclkksg ksrkenkfsa 1261 kklqctrlgs yiedrvnkyl krqnhpeage vfvrvvassd ktvevkpgmk srfvdsgems 1321 esfpyrtkal fafeeidgvd vcffgmhvqe ygsdcpfpnt rrvyisylds ihffkprllr 1381 tavyheilig yleyvkklgy vtghiwacpp segddyifhc hppdqkipkp krlqewyrkm 1441 ldkafaerii hdykdifkqa tedrltsaye lpyfegdfwp nvleesikel eqeeeerkke 1501 entassette gaqadsknak kknnkktnkn kssvsrankk kpgmpnvand lsqklyatme 1561 khkevffvih lhagpvvntl ppimdpdpll tcdlmdgrda fltlardkhw efsslrrckw 1621 stmcmlvelh nqgqdrfvyt cneckhhvet rwhctvcedf dlcincynsk ghehqmvkwg 1681 lgldddsnnq ggeankspqe srrlsiqrci qslvhacqcr nancslpscq kmkrvvqhtk 1741 gckrktnggc pvckqlialc cyhakhcqen kcpvpfclni khklrqqqiq qrlqqaqmmr 1801 rrmalmqgrg mppslpsptt sggpgtpnsq qlqqpntpqt sqalanqpqq thpnvaamvq 1861 afpnqpptpg sqgkpgpqss plpqqqsplp mppqqqpqps pqqqalkvak qiemmtkvkq 1921 qqqqqqqqqq qqqqqqqqqq qqdyrmsmng mpmnqprmmt smqmmgprgp qmvqnmqqgq 1981 wapgmamqnp qgpppqqvpq qqmamaqqqs qvaqtpqqaq miqralmqqq qqqqqqprqi 2041 qavmppqqvq pqapqqqgmq qrgvtsnitp galqdllrtl kspsspqqqq qvlnilksnp 2101 hlmaafikqr takyqanqpq qqqnpqamla sqqgmqnmaa mqpgsvqrpv mppqqqpqpq 2161 paatqamaal gsqgqmmnaa hngnqqlfrr qllrqmqqqq qhqqqqgamp pgqgrfpqpq 2221 gaasysqirv qqqmamqgga gpmgqmppma qmgqpgmgld aqqqqnlmqq rmlqqqqqqq 2281 qqmmkqqmgs paqaasmspq phmlggqpqg ahmpgqaman algnqvrspa pvqsprppsq 2341 qpphsspspr mqpqpsplhp gsshpslagp mpgpmdqahm ctaeqsamlp qlntpnrggl 2401 tndlnmdttg dtlekfvegl //
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