protein flightless-1 homolog isoform X1 [Homo sapiens]

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Biallelic variants in FLII cause pediatric cardiomyopathy by disrupting cardiomyocyte cell adhesion and myofibril organization. [JCI Insight. 2023]
Biallelic variants in FLII cause pediatric cardiomyopathy by disrupting cardiomyocyte cell adhesion and myofibril organization.
Ruijmbeek CW, Housley F, Idrees H, Housley MP, Pestel J, Keller L, Lai JK, der Linde HCV, Willemsen R, Piesker J, et al. JCI Insight. 2023 Sep 8; 8(17). Epub 2023 Sep 8.
Increased Expression of Flightless I in Cutaneous Squamous Cell Carcinoma Affects Wnt/β-Catenin Signaling Pathway. [Int J Mol Sci. 2021]
Increased Expression of Flightless I in Cutaneous Squamous Cell Carcinoma Affects Wnt/β-Catenin Signaling Pathway.
Yang GN, Strudwick XL, Bonder CS, Kopecki Z, Cowin AJ. Int J Mol Sci. 2021 Dec 8; 22(24). Epub 2021 Dec 8.
Flightless I Homolog Reverses Enzalutamide Resistance through PD-L1-Mediated Immune Evasion in Prostate Cancer. [Cancer Immunol Res. 2021]
Flightless I Homolog Reverses Enzalutamide Resistance through PD-L1-Mediated Immune Evasion in Prostate Cancer.
Ruan H, Bao L, Tao Z, Chen K. Cancer Immunol Res. 2021 Jul; 9(7):838-852. Epub 2021 May 19.

RefSeq genomic sequence
See the genomic reference sequence for the FLII gene (NG_023243.1).
RefSeq mRNA
See reference mRNA sequence for the FLII gene (XM_005256555.5).
RefSeq protein isoforms
See 12 reference sequence protein isoforms for the FLII gene.

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Protein