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MULTISPECIES: MFS transporter [Enterobacter]

NCBI Reference Sequence: WP_049119990.1

Identical Proteins FASTA Graphics 

LOCUS       WP_049119990             433 aa            linear   BCT 12-JAN-2025
DEFINITION  MULTISPECIES: MFS transporter [Enterobacter].
ACCESSION   WP_049119990
VERSION     WP_049119990.1
KEYWORDS    RefSeq.
SOURCE      Enterobacter
  ORGANISM  Enterobacter
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 433)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 433)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 433)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13022908
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Enterobacter"
                     /db_xref="taxon:547"
     Protein         1..433
                     /product="MFS transporter"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=47467
     Region          22..423
                     /region_name="MFS_ExuT_GudP_like"
                     /note="Hexuronate transporter, Glucarate transporter, and
                     similar transporters of the Major Facilitator Superfamily;
                     cd17319"
                     /db_xref="CDD:340877"
     Site            order(36..37,40..41,44,76,126..127,129..131,134,154,
                     157..158,161,249,252..253,256..258,261,289,293,351..352,
                     356,360,376,379..380,383..384,387)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340877"
ORIGIN      
        1 msqdinntva tsktrrvikn lrwyvlvlfl lgvtvnyitr nslgilapel keslgitteq
       61 yswivgafqi aytifqplcg wlidviglki gfmvcagiwa lmcifhagag swlhlailrf
      121 fmgaseaaat panaktigew fpkserpvaa gwagvgfsig amlappiiyf ahasfgwqga
      181 fmftgvlall wvilwwafyh npeqhpnlsr delafikqdn epapvklpfl talktvsknk
      241 rfygiaipaf maepawavls fwvplylake hgmdlkqiam fawlpflaad lgsvasgylt
      301 rlytrwfgcs rvnsvvassv tgaflmisla vvavtrdpyi tivlisiggf ghqiiscmls
      361 alvvesfdkg qmatvngmrg saawiasflf slligvtadk igfnplfiam gffdligalf
      421 lvafiaerra kra
//
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