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NCBI Reference Sequence: WP_001254032.1
Identical Proteins FASTA Graphics
Download a prokaryotic data package including protein sequence and gene sequence for all annotated locations for this protein as a zip archive.
LOCUS WP_001254032 501 aa linear BCT 23-JUL-2024 DEFINITION S49 family peptidase [Escherichia coli]. ACCESSION WP_001254032 VERSION WP_001254032.1 KEYWORDS RefSeq. SOURCE Escherichia coli ORGANISM Escherichia coli Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. REFERENCE 1 (residues 1 to 501) AUTHORS Rawlings,N.D. and Barrett,A.J. TITLE Families of serine peptidases JOURNAL Methods Enzymol 244, 19-61 (1994) PUBMED 7845208 REFERENCE 2 (residues 1 to 501) AUTHORS Rawlings,N.D. and Barrett,A.J. TITLE Evolutionary families of peptidases JOURNAL Biochem J 290 (Pt 1) (Pt 1), 205-218 (1993) PUBMED 8439290 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: Conserved Domain (CDD) Evidence Accession :: Domain architecture ID 10161638 Evidence Source :: NCBI SPARCLE ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..501 /organism="Escherichia coli" /db_xref="taxon:562" Protein 1..501 /product="S49 family peptidase" /EC_number="3.4.21.-" /GO_function="GO:0008233 - peptidase activity [Evidence IEA]" /GO_process="GO:0006508 - proteolysis [Evidence IEA]" /calculated_mol_wt=52261 Region 77..290 /region_name="S49_Sppa_36K_type" /note="Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; cd07022" /db_xref="CDD:132933" Site order(84,125,162,177,179,187..190,239,262..264,266,269) /site_type="other" /note="tandem repeat interface [polypeptide binding]" /db_xref="CDD:132933" Site order(104,111,137,203,205..209,237,241) /site_type="other" /note="oligomer interface [polypeptide binding]" /db_xref="CDD:132933" Site 162 /site_type="active" /note="active site residues [active]" /db_xref="CDD:132933" ORIGIN 1 mrrnlshiia aafnepllle payarvffca lgremgassl svpqqqvqfd apgmlaetde 61 ymaggkrpar vyrvvngiav lpvtgtlvhr lggmrpfsgm tgydgivacl qqamadsqvr 121 gilldidspg gqaagafdca dmiyrlrqqk pvwalcndta csaamllasa csrrlvtqts 181 rigsigvmms hvsyaghlaq agvditliys gahkvdgnqf ealpaevrqd mqqridaarr 241 mfaekvamft glsvdavtgt eaavfegqsg idagladelv nasdaisvma talnsnvrgg 301 tmpqltatea aaqenqrvmg iltcqeakgr eqlatmlagq qgmsveqara ilaaaapqqp 361 vastqseadr imaceeangr eqlaatlaam pemtvekarp ilaaspqada gpslrdqima 421 ldeakgaeaq aeqlaacpgm tvesaravla agsgkaepvs asttalferi manhspaavq 481 ggvpqtsadg dadvkmlmam p //
Whole sequence Selected region from: to:
Conserved Domains
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