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MULTISPECIES: TIR domain-containing protein [Enterobacteriaceae]

NCBI Reference Sequence: WP_000963206.1

Identical Proteins FASTA Graphics 

LOCUS       WP_000963206             299 aa            linear   BCT 06-SEP-2024
DEFINITION  MULTISPECIES: TIR domain-containing protein [Enterobacteriaceae].
ACCESSION   WP_000963206
VERSION     WP_000963206.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 299)
  AUTHORS   Tal,N., Morehouse,B.R., Millman,A., Stokar-Avihail,A., Avraham,C.,
            Fedorenko,T., Yirmiya,E., Herbst,E., Brandis,A., Mehlman,T.,
            Oppenheimer-Shaanan,Y., Keszei,A.F.A., Shao,S., Amitai,G.,
            Kranzusch,P.J. and Sorek,R.
  TITLE     Cyclic CMP and cyclic UMP mediate bacterial immunity against phages
  JOURNAL   Cell 184 (23), 5728-5739 (2021)
   PUBMED   34644530
REFERENCE   2  (residues 1 to 299)
  AUTHORS   Morehouse,B.R., Govande,A.A., Millman,A., Keszei,A.F.A., Lowey,B.,
            Ofir,G., Shao,S., Sorek,R. and Kranzusch,P.J.
  TITLE     STING cyclic dinucleotide sensing originated in bacteria
  JOURNAL   Nature 586 (7829), 429-433 (2020)
   PUBMED   32877915
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF021640.5
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF10137.14
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     Protein         1..299
                     /product="TIR domain-containing protein"
                     /GO_function="GO:0050135 - NADP+ nucleosidase activity
                     [Evidence IEA]"
                     /calculated_mol_wt=33530
     Region          151..288
                     /region_name="COG4271"
                     /note="Predicted nucleotide-binding protein containing TIR
                     -like domain [General function prediction only]"
                     /db_xref="CDD:443412"
ORIGIN      
        1 maidifqslk ncvfdlqrad vqnyqqplkq larllnsenl qsvnahltrn veldtflars
       61 edtessmags avlqwpdepa dilglkllli ekmaddnnfs fnfchtffyd rniiesirkf
      121 tsslvapfvr dyqlyvenqh dpepavfrpv srkifivhgh dndalqsvar fisrigleei
      181 ilserpdgsr tiiekfeaes gdvsfaivlm tpddsgsala sestrlrarq nvlyelgyfa
      241 gklgrgkvlv lrkgdieips dlagvlytel dehggwkrkl lselayagvp fdkdkalsa
//
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Protein clusters for WP_000963206.1

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