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NCBI Reference Sequence: WP_000963206.1
Identical Proteins FASTA Graphics
Download a prokaryotic data package including protein sequence and gene sequence for all annotated locations for this protein as a zip archive.
LOCUS WP_000963206 299 aa linear BCT 06-SEP-2024 DEFINITION MULTISPECIES: TIR domain-containing protein [Enterobacteriaceae]. ACCESSION WP_000963206 VERSION WP_000963206.1 KEYWORDS RefSeq. SOURCE Enterobacteriaceae ORGANISM Enterobacteriaceae Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales. REFERENCE 1 (residues 1 to 299) AUTHORS Tal,N., Morehouse,B.R., Millman,A., Stokar-Avihail,A., Avraham,C., Fedorenko,T., Yirmiya,E., Herbst,E., Brandis,A., Mehlman,T., Oppenheimer-Shaanan,Y., Keszei,A.F.A., Shao,S., Amitai,G., Kranzusch,P.J. and Sorek,R. TITLE Cyclic CMP and cyclic UMP mediate bacterial immunity against phages JOURNAL Cell 184 (23), 5728-5739 (2021) PUBMED 34644530 REFERENCE 2 (residues 1 to 299) AUTHORS Morehouse,B.R., Govande,A.A., Millman,A., Keszei,A.F.A., Lowey,B., Ofir,G., Shao,S., Sorek,R. and Kranzusch,P.J. TITLE STING cyclic dinucleotide sensing originated in bacteria JOURNAL Nature 586 (7829), 429-433 (2020) PUBMED 32877915 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: NF021640.5 Evidence Source :: EMBL-EBI Source Identifier :: PF10137.14 ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..299 /organism="Enterobacteriaceae" /db_xref="taxon:543" Protein 1..299 /product="TIR domain-containing protein" /GO_function="GO:0050135 - NADP+ nucleosidase activity [Evidence IEA]" /calculated_mol_wt=33530 Region 151..288 /region_name="COG4271" /note="Predicted nucleotide-binding protein containing TIR -like domain [General function prediction only]" /db_xref="CDD:443412" ORIGIN 1 maidifqslk ncvfdlqrad vqnyqqplkq larllnsenl qsvnahltrn veldtflars 61 edtessmags avlqwpdepa dilglkllli ekmaddnnfs fnfchtffyd rniiesirkf 121 tsslvapfvr dyqlyvenqh dpepavfrpv srkifivhgh dndalqsvar fisrigleei 181 ilserpdgsr tiiekfeaes gdvsfaivlm tpddsgsala sestrlrarq nvlyelgyfa 241 gklgrgkvlv lrkgdieips dlagvlytel dehggwkrkl lselayagvp fdkdkalsa //
Whole sequence Selected region from: to:
Conserved Domains
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