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NCBI Reference Sequence: WP_000527682.1
Identical Proteins FASTA Graphics
Download a prokaryotic data package including protein sequence and gene sequence for all annotated locations for this protein as a zip archive.
LOCUS WP_000527682 148 aa linear BCT 23-DEC-2024 DEFINITION MULTISPECIES: helix-turn-helix domain-containing protein [Enterobacterales]. ACCESSION WP_000527682 VERSION WP_000527682.1 KEYWORDS RefSeq. SOURCE Enterobacterales ORGANISM Enterobacterales Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria. REFERENCE 1 (residues 1 to 148) AUTHORS Aravind,L., Anantharaman,V., Balaji,S., Babu,M.M. and Iyer,L.M. TITLE The many faces of the helix-turn-helix domain: transcription regulation and beyond JOURNAL FEMS Microbiol Rev 29 (2), 231-262 (2005) PUBMED 15808743 REFERENCE 2 (residues 1 to 148) AUTHORS Wintjens,R. and Rooman,M. TITLE Structural classification of HTH DNA-binding domains and protein-DNA interaction modes JOURNAL J Mol Biol 262 (2), 294-313 (1996) PUBMED 8831795 REFERENCE 3 (residues 1 to 148) AUTHORS Brennan,R.G. and Matthews,B.W. TITLE The helix-turn-helix DNA binding motif JOURNAL J Biol Chem 264 (4), 1903-1906 (1989) PUBMED 2644244 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: Conserved Domain (CDD) Evidence Accession :: Domain architecture ID 10054599 Evidence Source :: NCBI SPARCLE ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..148 /organism="Enterobacterales" /db_xref="taxon:91347" Protein 1..148 /product="helix-turn-helix domain-containing protein" /GO_function="GO:0003677 - DNA binding [Evidence IEA]" /calculated_mol_wt=16434 Region 15..71 /region_name="HTH_XRE" /note="Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; cd00093" /db_xref="CDD:238045" Site order(19,23,47) /site_type="other" /note="non-specific DNA binding site [nucleotide binding]" /db_xref="CDD:238045" Site order(22,46) /site_type="active" /note="salt bridge [active]" /db_xref="CDD:238045" Site order(28..29,40,43,47..48) /site_type="other" /note="sequence-specific DNA binding site [nucleotide binding]" /db_xref="CDD:238045" ORIGIN 1 mgnnehevma dkqraerikk vilehstyee laektgisvs tlvriasgkt epkfsdiiqi 61 akitgadlnt laygyaldvk eeaterklit sadgytdeet tnahnfivwn irtlekqdil 121 alarqvsals sytystkmfm kkavsgee //
Whole sequence Selected region from: to:
Conserved Domains
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