RecName: Full=Bcl-2-binding component 3, isoforms 3/4; AltName: Full=J - Protein

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PUMA overexpression dissociates thioredoxin from ASK1 to activate the JNK/BCL-2/BCL-XL pathway augmenting apoptosis in ovarian cancer. [Biochim Biophys Acta Mol Basis...]
PUMA overexpression dissociates thioredoxin from ASK1 to activate the JNK/BCL-2/BCL-XL pathway augmenting apoptosis in ovarian cancer.
Chen Y, Li N, Yang J, Li K, Tang M, Zhao X, Guo W, Tong A, Nie C, Peng Y, et al. Biochim Biophys Acta Mol Basis Dis. 2022 Dec 1; 1868(12):166553. Epub 2022 Sep 17.
Expression of p53 up-regulated modulator of apoptosis (PUMA) in non-melanoma skin cancer of long-term immunosuppressed solid organ transplant recipients compared to immunocompetent patients. [Eur J Dermatol. 2021]
Expression of p53 up-regulated modulator of apoptosis (PUMA) in non-melanoma skin cancer of long-term immunosuppressed solid organ transplant recipients compared to immunocompetent patients.
Neuberger A, Menzer C, Volk N, Enk AH, Hadaschik EN, Lonsdorf AS. Eur J Dermatol. 2021 Oct 1; 31(5):609-615.
Recombinant human bone morphogenetic protein 2 and 7 inhibit the degeneration of intervertebral discs by blocking the Puma-dependent apoptotic signaling. [Int J Biol Sci. 2021]
Recombinant human bone morphogenetic protein 2 and 7 inhibit the degeneration of intervertebral discs by blocking the Puma-dependent apoptotic signaling.
Xie S, Zhao C, Chen W, Li G, Xiong Z, Tang X, Zhang F, Xiao H. Int J Biol Sci. 2021; 17(9):2367-2379. Epub 2021 Jun 11.

RefSeq genomic sequence
See the genomic reference sequence for the BBC3 gene (NG_031991.2).
RefSeq protein isoforms
See 10 reference sequence protein isoforms for the BBC3 gene.

Q96PG8 [Domain Mapping of Disease Mut...]
Q96PG8
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

RecName: Full=Bcl-2-binding component 3, isoforms 3/4; AltName: Full=JFY-1; AltN...
RecName: Full=Bcl-2-binding component 3, isoforms 3/4; AltName: Full=JFY-1; AltName: Full=p53 up-regulated modulator of apoptosis
gi|391738062|sp|Q96PG8.2|BBC3B_HUMA

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