RecName: Full=Calcium uptake protein 2, mitochondrial; Short=hMICU3; A - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.

A null mutation in MICU2 causes abnormal mitochondrial calcium homeostasis and a severe neurodevelopmental disorder. [Brain. 2017]
A null mutation in MICU2 causes abnormal mitochondrial calcium homeostasis and a severe neurodevelopmental disorder.
Shamseldin HE, Alasmari A, Salih MA, Samman MM, Mian SA, Alshidi T, Ibrahim N, Hashem M, Faqeih E, Al-Mohanna F, et al. Brain. 2017 Nov 1; 140(11):2806-2813.
The structure of the MICU1-MICU2 complex unveils the regulation of the mitochondrial calcium uniporter. [EMBO J. 2020]
The structure of the MICU1-MICU2 complex unveils the regulation of the mitochondrial calcium uniporter.
Wu W, Shen Q, Zhang R, Qiu Z, Wang Y, Zheng J, Jia Z. EMBO J. 2020 Oct 1; 39(19):e104285. Epub 2020 Aug 13.
Structure of the MICU1-MICU2 heterodimer provides insights into the gatekeeping threshold shift. [IUCrJ. 2020]
Structure of the MICU1-MICU2 heterodimer provides insights into the gatekeeping threshold shift.
Park J, Lee Y, Park T, Kang JY, Mun SA, Jin M, Yang J, Eom SH. IUCrJ. 2020 Mar 1; 7(Pt 2):355-365. Epub 2020 Feb 27.

RefSeq protein isoforms
See 9 reference sequence protein isoforms for the MICU2 gene.

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

Q8IYU8 [Domain Mapping of Disease Mut...]
Q8IYU8
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

Your browsing activity is empty.

Activity recording is turned off.

Protein