RecName: Full=Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2; - Protein

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DEGS2 polymorphism associated with cognition in schizophrenia is associated with gene expression in brain. [Transl Psychiatry. 2015]
DEGS2 polymorphism associated with cognition in schizophrenia is associated with gene expression in brain.
Ohi K, Ursini G, Li M, Shin JH, Ye T, Chen Q, Tao R, Kleinman JE, Hyde TM, Hashimoto R, et al. Transl Psychiatry. 2015 Apr 14; 5(4):e550. Epub 2015 Apr 14.
Identification of the human sphingolipid C4-hydroxylase, hDES2, and its up-regulation during keratinocyte differentiation. [FEBS Lett. 2004]
Identification of the human sphingolipid C4-hydroxylase, hDES2, and its up-regulation during keratinocyte differentiation.
Mizutani Y, Kihara A, Igarashi Y. FEBS Lett. 2004 Apr 9; 563(1-3):93-7.
Bifunctional DEGS2 has higher hydroxylase activity toward substrates with very-long-chain fatty acids in the production of phytosphingosine ceramides. [J Biol Chem. 2023]
Bifunctional DEGS2 has higher hydroxylase activity toward substrates with very-long-chain fatty acids in the production of phytosphingosine ceramides.
Ota A, Morita H, Naganuma T, Miyamoto M, Jojima K, Nojiri K, Matsuda J, Kihara A. J Biol Chem. 2023 Apr; 299(4):104603. Epub 2023 Mar 11.

RefSeq protein isoforms
See 3 reference sequence protein isoforms for the DEGS2 gene.

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Q6QHC5 [Domain Mapping of Disease Mut...]
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Protein