RecName: Full=SPRY domain-containing SOCS box protein 3; Short=SSB-3

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SPSB3 targets SNAIL for degradation in GSK-3β phosphorylation-dependent manner and regulates metastasis. [Oncogene. 2018]
SPSB3 targets SNAIL for degradation in GSK-3β phosphorylation-dependent manner and regulates metastasis.
Liu Y, Zhou H, Zhu R, Ding F, Li Y, Cao X, Liu Z. Oncogene. 2018 Feb 8; 37(6):768-776. Epub 2017 Oct 23.
The SPRY domain-containing SOCS box protein 1 (SSB-1) interacts with MET and enhances the hepatocyte growth factor-induced Erk-Elk-1-serum response element pathway. [J Biol Chem. 2005]
The SPRY domain-containing SOCS box protein 1 (SSB-1) interacts with MET and enhances the hepatocyte growth factor-induced Erk-Elk-1-serum response element pathway.
Wang D, Li Z, Messing EM, Wu G. J Biol Chem. 2005 Apr 22; 280(16):16393-401. Epub 2005 Feb 15.
The CRL5-SPSB3 ubiquitin ligase targets nuclear cGAS for degradation. [Nature. 2024]
The CRL5-SPSB3 ubiquitin ligase targets nuclear cGAS for degradation.
Xu P, Liu Y, Liu C, Guey B, Li L, Melenec P, Ricci J, Ablasser A. Nature. 2024 Mar; 627(8005):873-879. Epub 2024 Feb 28.

RefSeq protein isoforms
See 7 reference sequence protein isoforms for the SPSB3 gene.

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Q6PJ21 [Domain Mapping of Disease Mut...]
Q6PJ21
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