RecName: Full=Glycine--tRNA ligase; AltName: Full=Diadenosine tetrapho - Protein

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Compound heterozygosity for loss-of-function GARS variants results in a multisystem developmental syndrome that includes severe growth retardation. [Hum Mutat. 2017]
Compound heterozygosity for loss-of-function GARS variants results in a multisystem developmental syndrome that includes severe growth retardation.
Oprescu SN, Chepa-Lotrea X, Takase R, Golas G, Markello TC, Adams DR, Toro C, Gropman AL, Hou YM, Malicdan MCV, et al. Hum Mutat. 2017 Oct; 38(10):1412-1420. Epub 2017 Jul 14.
Crystal structures and biochemical analyses suggest a unique mechanism and role for human glycyl-tRNA synthetase in Ap4A homeostasis. [J Biol Chem. 2009]
Crystal structures and biochemical analyses suggest a unique mechanism and role for human glycyl-tRNA synthetase in Ap4A homeostasis.
Guo RT, Chong YE, Guo M, Yang XL. J Biol Chem. 2009 Oct 16; 284(42):28968-76. Epub 2009 Aug 26.
An ENU-induced mutation in mouse glycyl-tRNA synthetase (GARS) causes peripheral sensory and motor phenotypes creating a model of Charcot-Marie-Tooth type 2D peripheral neuropathy. [Dis Model Mech. 2009]
An ENU-induced mutation in mouse glycyl-tRNA synthetase (GARS) causes peripheral sensory and motor phenotypes creating a model of Charcot-Marie-Tooth type 2D peripheral neuropathy.
Achilli F, Bros-Facer V, Williams HP, Banks GT, AlQatari M, Chia R, Tucci V, Groves M, Nickols CD, Seburn KL, et al. Dis Model Mech. 2009 Jul-Aug; 2(7-8):359-73. Epub 2009 May 26.

RefSeq protein isoforms
See 2 reference sequence protein isoforms for the Gars1 gene.

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