NACK is an integral component of the Notch transcriptional activation complex and is critical for development and tumorigenesis.
Weaver KL, Alves-Guerra MC, Jin K, Wang Z, Han X, Ranganathan P, Zhu X, DaSilva T, Liu W, Ratti F, et al. Cancer Res. 2014 Sep 1; 74(17):4741-51. Epub 2014 Jul 18.