RecName: Full=Mesothelin; AltName: Full=CAK1 antigen; AltName: Full=Pr - Protein

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Mesothelin-based CAR-T cells exhibit potent antitumor activity against ovarian cancer. [J Transl Med. 2024]
Mesothelin-based CAR-T cells exhibit potent antitumor activity against ovarian cancer.
Guo J, Zeng X, Zhu Y, Yang D, Zhao X. J Transl Med. 2024 Apr 18; 22(1):367. Epub 2024 Apr 18.
Enhanced Expression of Glycolytic Enzymes and Succinate Dehydrogenase Complex Flavoprotein Subunit A by Mesothelin Promotes Glycolysis and Mitochondrial Respiration in Myeloblasts of Acute Myeloid Leukemia. [Int J Mol Sci. 2024]
Enhanced Expression of Glycolytic Enzymes and Succinate Dehydrogenase Complex Flavoprotein Subunit A by Mesothelin Promotes Glycolysis and Mitochondrial Respiration in Myeloblasts of Acute Myeloid Leukemia.
Jang Y, Koh JS, Park JH, Choi S, Duong PTT, Heo BY, Lee SW, Kim JY, Lee MW, Kim SH, et al. Int J Mol Sci. 2024 Feb 10; 25(4). Epub 2024 Feb 10.
Tumor resistance to anti-mesothelin CAR-T cells caused by binding to shed mesothelin is overcome by targeting a juxtamembrane epitope. [Proc Natl Acad Sci U S A. 2024]
Tumor resistance to anti-mesothelin CAR-T cells caused by binding to shed mesothelin is overcome by targeting a juxtamembrane epitope.
Liu XF, Onda M, Schlomer J, Bassel L, Kozlov S, Tai CH, Zhou Q, Liu W, Tsao HE, Hassan R, et al. Proc Natl Acad Sci U S A. 2024 Jan 23; 121(4):e2317283121. Epub 2024 Jan 16.

RefSeq protein isoforms
See 3 reference sequence protein isoforms for the MSLN gene.

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Dryad Digital Repository [Dryad Digital Repository]
Dryad Digital Repository
Q13421 [Domain Mapping of Disease Mut...]
Q13421
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

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Protein