RecName: Full=Tyrosine-protein phosphatase non-receptor type 11; AltNa - Protein

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Allosteric inhibitor of SHP2 enhances macrophage endocytosis and bacteria elimination by increasing caveolae activation and protects against bacterial sepsis. [Pharmacol Res. 2024]
Allosteric inhibitor of SHP2 enhances macrophage endocytosis and bacteria elimination by increasing caveolae activation and protects against bacterial sepsis.
Li T, Xu B, Li W, Cheng X, Tantai W, Zheng H, Zhao L, Li N, Han C. Pharmacol Res. 2024 Mar; 201:107096. Epub 2024 Feb 4.
Hepatic protein tyrosine phosphatase Shp2 disruption mitigates the adverse effects of ethanol in the liver by modulating oxidative stress and ERK signaling. [Life Sci. 2024]
Hepatic protein tyrosine phosphatase Shp2 disruption mitigates the adverse effects of ethanol in the liver by modulating oxidative stress and ERK signaling.
Hsu MF, LeBleu G, Flores L, Parkhurst A, Nagy LE, Haj FG. Life Sci. 2024 Mar 1; 340:122451. Epub 2024 Jan 20.
Deciphering a critical role of uterine epithelial SHP2 in parturition initiation at single cell resolution. [Nat Commun. 2023]
Deciphering a critical role of uterine epithelial SHP2 in parturition initiation at single cell resolution.
Liu M, Ji M, Cheng J, Li Y, Tian Y, Zhao H, Wang Y, Zhu S, Zhang L, Xu X, et al. Nat Commun. 2023 Nov 14; 14(1):7356. Epub 2023 Nov 14.

RefSeq protein isoforms
See 2 reference sequence protein isoforms for the Ptpn11 gene.

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Mouse Genome Informatics (MGI) [Mouse Genome Informatics (MGI)]
Mouse Genome Informatics (MGI)
Reactome [Reactome]
Reactome

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Protein