RecName: Full=Thyroid peroxidase; Short=TPO; Flags: Precursor

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Articles about the TPO gene

Is There a Link between Thyroid Peroxidase Gene Promoter Polymorphisms and Autoimmune Thyroiditis in the Polish Population? [Int J Mol Sci. 2024]
Is There a Link between Thyroid Peroxidase Gene Promoter Polymorphisms and Autoimmune Thyroiditis in the Polish Population?
Lacka K, Maciejewski A, Jarecki P, Herman W, Lacki JK, Żaba R, Kowalczyk MJ. Int J Mol Sci. 2024 Mar 14; 25(6). Epub 2024 Mar 14.
Disulfide Bonds of Thyroid Peroxidase Are Critical Elements for Subcellular Localization, Proteasome-Dependent Degradation, and Enzyme Activity. [Thyroid. 2024]
Disulfide Bonds of Thyroid Peroxidase Are Critical Elements for Subcellular Localization, Proteasome-Dependent Degradation, and Enzyme Activity.
Iwasaki H, Suwanai H, Yakou F, Sakai H, Ishii K, Hara N, Buckle AM, Kanekura K, Miyagi T, Narumi S, et al. Thyroid. 2024 May; 34(5):659-667. Epub 2024 Apr 11.
Homozygous Mutations in Thyroid Peroxidase (TPO) in Hypothyroidism with Intellectual Disability, Developmental Delay, and Hearing and Ocular Anomalies in Two Families: Severe Manifestation of Untreated TPO-deficiency Poses a Diagnostic Dilemma. [Yale J Biol Med. 2023]
Homozygous Mutations in Thyroid Peroxidase (TPO) in Hypothyroidism with Intellectual Disability, Developmental Delay, and Hearing and Ocular Anomalies in Two Families: Severe Manifestation of Untreated TPO-deficiency Poses a Diagnostic Dilemma.
Naqvi SF, Yıldız-Bölükbaşı E, Afzal M, Nalbant G, Mumtaz S, Tolun A, Malik S. Yale J Biol Med. 2023 Sep; 96(3):347-365. Epub 2023 Sep 29.

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Reference sequence information

RefSeq genomic sequence
See the genomic reference sequence for the TPO gene (NG_011581.2).
RefSeq protein isoforms
See 33 reference sequence protein isoforms for the TPO gene.

More about the TPO gene

This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. T...
Also Known As: MSA, TDH2A, TPX

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Dryad Digital Repository [Dryad Digital Repository]
Dryad Digital Repository
P07202 [Domain Mapping of Disease Mut...]
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Domain Mapping of Disease Mutations
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Articles about the TPO gene

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