mitochondrial inner membrane m-AAA protease component paraplegin isofo - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

A novel compound heterozygous SPG7 variant is associated with progressive spastic ataxia and persecutory delusions found in Chinese patients: two case reports. [BMC Neurol. 2022]
A novel compound heterozygous SPG7 variant is associated with progressive spastic ataxia and persecutory delusions found in Chinese patients: two case reports.
Wang S, Wang Y, Wu Y, Zhang J, Zhang W, Li C, Song X. BMC Neurol. 2022 May 30; 22(1):200. Epub 2022 May 30.
A novel homozygous variant in the SPG7 gene presenting with childhood optic nerve atrophy. [Am J Ophthalmol Case Rep. 2022]
A novel homozygous variant in the SPG7 gene presenting with childhood optic nerve atrophy.
Eriksen KO, Wigers AR, Wedding IM, Erichsen AK, Barøy T, Søberg K, Jørstad ØK. Am J Ophthalmol Case Rep. 2022 Jun; 26:101400. Epub 2022 Feb 16.
Clinical and genetic characteristics of 21 Spanish patients with biallelic pathogenic SPG7 mutations. [J Neurol Sci. 2021]
Clinical and genetic characteristics of 21 Spanish patients with biallelic pathogenic SPG7 mutations.
Baviera-Muñoz R, Campins-Romeu M, Carretero-Vilarroig L, Sastre-Bataller I, Martínez-Torres I, Vázquez-Costa JF, Muelas N, Sevilla T, Vílchez JJ, Aller E, et al. J Neurol Sci. 2021 Oct 15; 429:118062. Epub 2021 Aug 30.

RefSeq genomic sequence
See the genomic reference sequence for the SPG7 gene (NG_008082.1).
RefSeq mRNA
See reference mRNA sequence for the SPG7 gene (NM_199367.3).
RefSeq protein isoforms
See 14 reference sequence protein isoforms for the SPG7 gene.

BioProject
Proteins related to BioProjects
Nucleotide
Nucleotide sequence from coding region
PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CCDS
Link to Consensus CDS
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Encoding mRNA
Link from protein to encoding mRNA
Gene
Link to related Genes
Genome
Genome record encoding protein sequence
OMIM
OMIM records associated with protein sequence
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures
SNP
Related SNPs

Ensembl [Ensembl]
Ensembl
OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

Your browsing activity is empty.

Activity recording is turned off.

Protein