LOCUS NP_666882 312 aa linear ROD 26-OCT-2024
DEFINITION olfactory receptor family 6 subfamily C member 69C [Mus musculus].
ACCESSION NP_666882
VERSION NP_666882.1
DBSOURCE REFSEQ: accession NM_146671.1
KEYWORDS RefSeq; RefSeq Select.
SOURCE Mus musculus (house mouse)
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE 1 (residues 1 to 312)
AUTHORS Olender,T., Jones,T.E.M., Bruford,E. and Lancet,D.
TITLE A unified nomenclature for vertebrate olfactory receptors
JOURNAL BMC Evol Biol 20 (1), 42 (2020)
PUBMED 32295537
REMARK Publication Status: Online-Only
REFERENCE 2 (residues 1 to 312)
AUTHORS Young,J.M., Shykind,B.M., Lane,R.P., Tonnes-Priddy,L., Ross,J.A.,
Walker,M., Williams,E.M. and Trask,B.J.
TITLE Odorant receptor expressed sequence tags demonstrate olfactory
expression of over 400 genes, extensive alternate splicing and
unequal expression levels
JOURNAL Genome Biol 4 (11), R71 (2003)
PUBMED 14611657
REFERENCE 3 (residues 1 to 312)
AUTHORS Young,J.M., Friedman,C., Williams,E.M., Ross,J.A., Tonnes-Priddy,L.
and Trask,B.J.
TITLE Different evolutionary processes shaped the mouse and human
olfactory receptor gene families
JOURNAL Hum Mol Genet 11 (5), 535-546 (2002)
PUBMED 11875048
REMARK Erratum:[Hum Mol Genet. 2002 Jul 1;11(14):1683.]
REFERENCE 4 (residues 1 to 312)
AUTHORS Zhang,X. and Firestein,S.
TITLE The olfactory receptor gene superfamily of the mouse
JOURNAL Nat Neurosci 5 (2), 124-133 (2002)
PUBMED 11802173
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence was derived from AY073424.1.
Summary: Olfactory receptors interact with odorant molecules in the
nose, to initiate a neuronal response that triggers the perception
of a smell. The olfactory receptor proteins are members of a large
family of G-protein-coupled receptors (GPCR) arising from single
coding-exon genes. Olfactory receptors share a 7-transmembrane
domain structure with many neurotransmitter and hormone receptors
and are responsible for the recognition and G protein-mediated
transduction of odorant signals. The olfactory receptor gene family
is the largest in the genome. [provided by RefSeq, Jul 2008].
##Evidence-Data-START##
Transcript is intronless :: BC127972.1 [ECO:0000345]
##Evidence-Data-END##
##RefSeq-Attributes-START##
RefSeq Select criteria :: based on single protein-coding transcript
##RefSeq-Attributes-END##
FEATURES Location/Qualifiers
source 1..312
/organism="Mus musculus"
/db_xref="taxon:10090"
/chromosome="10"
/map="10 77.7 cM"
Protein 1..312
/product="olfactory receptor family 6 subfamily C member
69C"
/note="olfactory receptor MOR113-2;
GA_x6K02T2PULF-11745102-11746040; olfactory receptor 822"
/calculated_mol_wt=35104
Region 23..292
/region_name="7tmA_OR6C-like"
/note="olfactory receptor subfamily 6C and related
proteins, member of the class A family of
seven-transmembrane G protein-coupled receptors; cd15912"
/db_xref="CDD:320578"
Region 24..50
/region_name="TM helix 1"
/note="TM helix 1 [structural motif]"
/db_xref="CDD:320578"
Region 57..83
/region_name="TM helix 2"
/note="TM helix 2 [structural motif]"
/db_xref="CDD:320578"
Site order(79,82..83,95..100,102..103,106,151,153..157,193,
196..198,200..202,204..205,250,253..254,256..257,260,
266..267,269..271,274,277..278)
/site_type="other"
/note="putative ligand binding pocket [chemical binding]"
/db_xref="CDD:320578"
Region 95..125
/region_name="TM helix 3"
/note="TM helix 3 [structural motif]"
/db_xref="CDD:320578"
Region 138..159
/region_name="TM helix 4"
/note="TM helix 4 [structural motif]"
/db_xref="CDD:320578"
Region 193..223
/region_name="TM helix 5"
/note="TM helix 5 [structural motif]"
/db_xref="CDD:320578"
Region 230..260
/region_name="TM helix 6"
/note="TM helix 6 [structural motif]"
/db_xref="CDD:320578"
Region 267..292
/region_name="TM helix 7"
/note="TM helix 7 [structural motif]"
/db_xref="CDD:320578"
CDS 1..312
/gene="Or6c69c"
/gene_synonym="MOR113-2; Olfr822"
/coded_by="NM_146671.1:1..939"
/db_xref="CCDS:CCDS24347.1"
/db_xref="GeneID:258666"
/db_xref="MGI:MGI:3030656"
ORIGIN
1 mknhtrvtif iiagltddpq wkvvlfifll ltyllsitgn ltiitltlvd thlktpmyff
61 lrnfsfleis ytttcipkll vtmatgdkti synncaaqvf fafllgasef yllaamsydr
121 yvaickplhy mtimsnkvcv qlvlscwlis fliifpplvl glnldfcasn iidhfycdtt
181 pllqisctdt qlietiafis alvtllltlv mviisytyia mtilkipsts qrkkafstcs
241 shmivisisy gscifmyvkp svkqrvsisk gisvlntsva pllnpfiytl rnqqvkrafi
301 ntvhrivsfs kk
//