EGF-containing fibulin-like extracellular matrix protein 2 precursor [ - Protein

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Whole-exome sequencing uncovers a novel EFEMP2 gene variant (c.C247T) associated with dominant nonsyndromic thoracic aortic aneurysm. [Lab Med. 2024]
Whole-exome sequencing uncovers a novel EFEMP2 gene variant (c.C247T) associated with dominant nonsyndromic thoracic aortic aneurysm.
Sadeghipour P, Valuian M, Ghasemi S, Rafiee F, Pourirahim M, Mahmoodian M, Maleki M, Kalayinia S. Lab Med. 2024 Jul 3; 55(4):447-453.
EFEMP2 upregulates PD-L1 expression via EGFR/ERK1/2/c-Jun signaling to promote the invasion of ovarian cancer cells. [Cell Mol Biol Lett. 2023]
EFEMP2 upregulates PD-L1 expression via EGFR/ERK1/2/c-Jun signaling to promote the invasion of ovarian cancer cells.
Shen X, Jin X, Fang S, Chen J. Cell Mol Biol Lett. 2023 Jul 7; 28(1):53. Epub 2023 Jul 7.
EFEMP2 increases the invasion ability of cervical cancer cells by promoting EMT via the Raf/MEK/ERK signaling pathway. [Neoplasma. 2022]
EFEMP2 increases the invasion ability of cervical cancer cells by promoting EMT via the Raf/MEK/ERK signaling pathway.
Li N, Ji GX, Yang ZY. Neoplasma. 2022 Sep; 69(5):1185-1197. Epub 2022 Aug 24.

RefSeq genomic sequence
See the genomic reference sequence for the EFEMP2 gene (NG_012304.2).
RefSeq mRNA
See reference mRNA sequence for the EFEMP2 gene (NM_016938.5).

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NP_058634 [Domain Mapping of Disease Mut...]
NP_058634
Domain Mapping of Disease Mutations
Ensembl [Ensembl]
Ensembl
GlyGen glycoinformatics resource [GlyGen glycoinformatics resou...]
GlyGen glycoinformatics resource
OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
Find Quality Antibodies [GeneTex Inc]
Find Quality Antibodies
GeneTex Inc

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