2-hydroxyacyl-CoA lyase 1 isoform a [Homo sapiens]

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Articles about the HACL1 gene

Role of thiamine pyrophosphate in oligomerisation, functioning and import of peroxisomal 2-hydroxyacyl-CoA lyase. [Biochim Biophys Acta. 2011]
Role of thiamine pyrophosphate in oligomerisation, functioning and import of peroxisomal 2-hydroxyacyl-CoA lyase.
Fraccascia P, Casteels M, De Schryver E, Van Veldhoven PP. Biochim Biophys Acta. 2011 Oct; 1814(10):1226-33. Epub 2011 Jun 25.
Breakdown of 2-hydroxylated straight chain fatty acids via peroxisomal 2-hydroxyphytanoyl-CoA lyase: a revised pathway for the alpha-oxidation of straight chain fatty acids. [J Biol Chem. 2005]
Breakdown of 2-hydroxylated straight chain fatty acids via peroxisomal 2-hydroxyphytanoyl-CoA lyase: a revised pathway for the alpha-oxidation of straight chain fatty acids.
Foulon V, Sniekers M, Huysmans E, Asselberghs S, Mahieu V, Mannaerts GP, Van Veldhoven PP, Casteels M. J Biol Chem. 2005 Mar 18; 280(11):9802-12. Epub 2005 Jan 11.
Purification, molecular cloning, and expression of 2-hydroxyphytanoyl-CoA lyase, a peroxisomal thiamine pyrophosphate-dependent enzyme that catalyzes the carbon-carbon bond cleavage during alpha-oxidation of 3-methyl-branched fatty acids. [Proc Natl Acad Sci U S A. 1999]
Purification, molecular cloning, and expression of 2-hydroxyphytanoyl-CoA lyase, a peroxisomal thiamine pyrophosphate-dependent enzyme that catalyzes the carbon-carbon bond cleavage during alpha-oxidation of 3-methyl-branched fatty acids.
Foulon V, Antonenkov VD, Croes K, Waelkens E, Mannaerts GP, Van Veldhoven PP, Casteels M. Proc Natl Acad Sci U S A. 1999 Aug 31; 96(18):10039-44.

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Reference sequence information

RefSeq protein isoforms
See 4 reference sequence protein isoforms for the HACL1 gene.

More about the HACL1 gene

Enables several functions, including 2-hydroxyacyl-CoA lyase activity; ATP binding activity; and cation binding activity. Involved in fatty ...
Also Known As: 2-HPCL, HPCL, HPCL2, PH...

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