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collagen alpha-1(X) chain precursor [Mus musculus]

NCBI Reference Sequence: NP_034055.1

Identical Proteins FASTA Graphics 

LOCUS       NP_034055                680 aa            linear   ROD 19-NOV-2024
DEFINITION  collagen alpha-1(X) chain precursor [Mus musculus].
ACCESSION   NP_034055
VERSION     NP_034055.1
DBSOURCE    REFSEQ: accession NM_009925.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 680)
  AUTHORS   Dinesh,N.E.H., Baratang,N., Rosseau,J., Mohapatra,R., Li,L.,
            Mahalingam,R., Tiedemann,K., Campeau,P.M. and Reinhardt,D.P.
  TITLE     Fibronectin isoforms promote postnatal skeletal development
  JOURNAL   Matrix Biol 133, 86-102 (2024)
   PUBMED   39159790
REFERENCE   2  (residues 1 to 680)
  AUTHORS   Li,Q., Jiang,S., Lei,K., Han,H., Chen,Y., Lin,W., Xiong,Q., Qi,X.,
            Gan,X., Sheng,R., Wang,Y., Zhang,Y., Ma,J., Li,T., Lin,S., Zhou,C.,
            Chen,D. and Yuan,Q.
  TITLE     Metabolic rewiring during bone development underlies tRNA
            m7G-associated primordial dwarfism
  JOURNAL   J Clin Invest 134 (20), e177220 (2024)
   PUBMED   39255038
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 680)
  AUTHORS   Saeki,N., Inui-Yamamoto,C., Ikeda,Y., Kanai,R., Hata,K., Itoh,S.,
            Inubushi,T., Akiyama,S., Ohba,S. and Abe,M.
  TITLE     Deletion of Trps1 regulatory elements recapitulates postnatal hip
            joint abnormalities and growth retardation of Trichorhinophalangeal
            syndrome in mice
  JOURNAL   Hum Mol Genet 33 (18), 1618-1629 (2024)
   PUBMED   38899779
REFERENCE   4  (residues 1 to 680)
  AUTHORS   Almubarak,A., Zhang,Q., Zhang,C.H., Abdelwahab,N., Kume,T.,
            Lassar,A.B. and Berry,F.B.
  TITLE     FOXC1 and FOXC2 regulate growth plate chondrocyte maturation
            towards hypertrophy in the embryonic mouse limb skeleton
  JOURNAL   Development 151 (16) (2024)
   PUBMED   39012257
REFERENCE   5  (residues 1 to 680)
  AUTHORS   Lv,Y., Wang,Q., Lin,C., Zheng,X., Zhang,Y. and Hu,X.
  TITLE     Overexpression of Fgf18 in cranial neural crest cells recapitulates
            Pierre Robin sequence in mice
  JOURNAL   Front Cell Dev Biol 12, 1376814 (2024)
   PUBMED   38694818
  REMARK    Publication Status: Online-Only
REFERENCE   6  (residues 1 to 680)
  AUTHORS   Gack,S., Vallon,R., Schmidt,J., Grigoriadis,A., Tuckermann,J.,
            Schenkel,J., Weiher,H., Wagner,E.F. and Angel,P.
  TITLE     Expression of interstitial collagenase during skeletal development
            of the mouse is restricted to osteoblast-like cells and
            hypertrophic chondrocytes
  JOURNAL   Cell Growth Differ 6 (6), 759-767 (1995)
   PUBMED   7669731
REFERENCE   7  (residues 1 to 680)
  AUTHORS   Luo,G., D'Souza,R., Hogue,D. and Karsenty,G.
  TITLE     The matrix Gla protein gene is a marker of the chondrogenesis cell
            lineage during mouse development
  JOURNAL   J Bone Miner Res 10 (2), 325-334 (1995)
   PUBMED   7754814
REFERENCE   8  (residues 1 to 680)
  AUTHORS   Giros,B., Pohl,M., Rochelle,J.M. and Seldin,M.F.
  TITLE     Chromosomal localization of opioid peptide and receptor genes in
            the mouse
  JOURNAL   Life Sci 56 (18), PL369-PL375 (1995)
   PUBMED   7752808
REFERENCE   9  (residues 1 to 680)
  AUTHORS   Apte,S.S., Seldin,M.F., Hayashi,M. and Olsen,B.R.
  TITLE     Cloning of the human and mouse type X collagen genes and mapping of
            the mouse type X collagen gene to chromosome 10
  JOURNAL   Eur J Biochem 206 (1), 217-224 (1992)
   PUBMED   1587271
REFERENCE   10 (residues 1 to 680)
  AUTHORS   Elima,K., Metsaranta,M., Kallio,J., Perala,M., Eerola,I.,
            Garofalo,S., De Crombrugghe,B. and Vuorio,E.
  TITLE     Specific hybridization probes for mouse alpha 2(IX) and alpha 1(X)
            collagen mRNAs
  JOURNAL   Biochim Biophys Acta 1130 (1), 78-80 (1992)
   PUBMED   1543751
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY141606.1, CN664467.1, AC153960.3 and CJ326431.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The extent of this transcript is
            supported by transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AI663040.1, BY771794.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..680
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 18.85 cM"
     Protein         1..680
                     /product="collagen alpha-1(X) chain precursor"
                     /note="collagen alpha-1(X) chain; procollagen, type X,
                     alpha 1"
                     /calculated_mol_wt=64710
     sig_peptide     1..18
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2084
     mat_peptide     19..680
                     /product="Collagen alpha-1(X) chain. /id=PRO_0000005771"
                     /note="propagated from UniProtKB/Swiss-Prot (Q05306.1)"
                     /calculated_mol_wt=64710
     Region          19..56
                     /region_name="Nonhelical region (NC2)"
                     /note="propagated from UniProtKB/Swiss-Prot (Q05306.1)"
     Region          54..531
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q05306.1)"
     Region          57..519
                     /region_name="Triple-helical region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q05306.1)"
     Region          <279..>478
                     /region_name="gly_rich_SclB"
                     /note="LPXTG-anchored collagen-like adhesin Scl2/SclB;
                     NF038329"
                     /db_xref="CDD:468478"
     Region          520..680
                     /region_name="Nonhelical region (NC1)"
                     /note="propagated from UniProtKB/Swiss-Prot (Q05306.1)"
     Region          545..680
                     /region_name="C1Q"
                     /note="Complement component C1q domain; smart00110"
                     /db_xref="CDD:128420"
     CDS             1..680
                     /gene="Col10a1"
                     /gene_synonym="Col10; Col10a-1"
                     /coded_by="NM_009925.4:79..2121"
                     /db_xref="CCDS:CCDS23780.1"
                     /db_xref="GeneID:12813"
                     /db_xref="MGI:MGI:88445"
ORIGIN      
        1 mlpqipflll mfltlvhgmf yaeryqtptg ikgplaspkt qyfipyaiks kgipvrgeqg
       61 ipgppgptgp rghpgpsgpp gkpgygspgl qgepglpgpp gisatgkpgl pgppgkpger
      121 gpyghkgdig paglpgprgp pgppgipgpa gisvpgkpgq qgltgapgpr gfpgekgaqg
      181 apgvngrkge tgygspgrpg erglpgpqgp igppgpsgvg rrgengfpgq pgikgdrgfp
      241 gemgpsgppg pqgppgkqgr egigkpgaig spgqpgipge kghpgapgia gppgapgfgk
      301 qglpglrgqr gpaglpgapg akgergpagh pgepglpgsp gnmgpqgpkg ipgnhgipga
      361 kgeiglvgpa gppgargarg ppgldgktgy pgepglngpk gnpglpgqkg dpgvggtpgl
      421 rgpvgpvgak gvpghngeag prgepgipgt rgptgppgvp gfpgskgdpg npgapgpagi
      481 atkglngptg ppgppgprgh sgepglpgpp gppgppgqav mpdgfikagq rprlsgmplv
      541 sanhgvtgmp vsaftvilsk aypavgapip fdeilynrqq hydprsgift ckipgiyyfs
      601 yhvhvkgthv wvglykngtp tmytydeysk gyldqasgsa imeltendqv wlqlpnaesn
      661 glysseyvhs sfsgflvapm
//
Feature
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