LOCUS NP_034055 680 aa linear ROD 19-NOV-2024
DEFINITION collagen alpha-1(X) chain precursor [Mus musculus].
ACCESSION NP_034055
VERSION NP_034055.1
DBSOURCE REFSEQ: accession NM_009925.4
KEYWORDS RefSeq; RefSeq Select.
SOURCE Mus musculus (house mouse)
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE 1 (residues 1 to 680)
AUTHORS Dinesh,N.E.H., Baratang,N., Rosseau,J., Mohapatra,R., Li,L.,
Mahalingam,R., Tiedemann,K., Campeau,P.M. and Reinhardt,D.P.
TITLE Fibronectin isoforms promote postnatal skeletal development
JOURNAL Matrix Biol 133, 86-102 (2024)
PUBMED 39159790
REFERENCE 2 (residues 1 to 680)
AUTHORS Li,Q., Jiang,S., Lei,K., Han,H., Chen,Y., Lin,W., Xiong,Q., Qi,X.,
Gan,X., Sheng,R., Wang,Y., Zhang,Y., Ma,J., Li,T., Lin,S., Zhou,C.,
Chen,D. and Yuan,Q.
TITLE Metabolic rewiring during bone development underlies tRNA
m7G-associated primordial dwarfism
JOURNAL J Clin Invest 134 (20), e177220 (2024)
PUBMED 39255038
REMARK Publication Status: Online-Only
REFERENCE 3 (residues 1 to 680)
AUTHORS Saeki,N., Inui-Yamamoto,C., Ikeda,Y., Kanai,R., Hata,K., Itoh,S.,
Inubushi,T., Akiyama,S., Ohba,S. and Abe,M.
TITLE Deletion of Trps1 regulatory elements recapitulates postnatal hip
joint abnormalities and growth retardation of Trichorhinophalangeal
syndrome in mice
JOURNAL Hum Mol Genet 33 (18), 1618-1629 (2024)
PUBMED 38899779
REFERENCE 4 (residues 1 to 680)
AUTHORS Almubarak,A., Zhang,Q., Zhang,C.H., Abdelwahab,N., Kume,T.,
Lassar,A.B. and Berry,F.B.
TITLE FOXC1 and FOXC2 regulate growth plate chondrocyte maturation
towards hypertrophy in the embryonic mouse limb skeleton
JOURNAL Development 151 (16) (2024)
PUBMED 39012257
REFERENCE 5 (residues 1 to 680)
AUTHORS Lv,Y., Wang,Q., Lin,C., Zheng,X., Zhang,Y. and Hu,X.
TITLE Overexpression of Fgf18 in cranial neural crest cells recapitulates
Pierre Robin sequence in mice
JOURNAL Front Cell Dev Biol 12, 1376814 (2024)
PUBMED 38694818
REMARK Publication Status: Online-Only
REFERENCE 6 (residues 1 to 680)
AUTHORS Gack,S., Vallon,R., Schmidt,J., Grigoriadis,A., Tuckermann,J.,
Schenkel,J., Weiher,H., Wagner,E.F. and Angel,P.
TITLE Expression of interstitial collagenase during skeletal development
of the mouse is restricted to osteoblast-like cells and
hypertrophic chondrocytes
JOURNAL Cell Growth Differ 6 (6), 759-767 (1995)
PUBMED 7669731
REFERENCE 7 (residues 1 to 680)
AUTHORS Luo,G., D'Souza,R., Hogue,D. and Karsenty,G.
TITLE The matrix Gla protein gene is a marker of the chondrogenesis cell
lineage during mouse development
JOURNAL J Bone Miner Res 10 (2), 325-334 (1995)
PUBMED 7754814
REFERENCE 8 (residues 1 to 680)
AUTHORS Giros,B., Pohl,M., Rochelle,J.M. and Seldin,M.F.
TITLE Chromosomal localization of opioid peptide and receptor genes in
the mouse
JOURNAL Life Sci 56 (18), PL369-PL375 (1995)
PUBMED 7752808
REFERENCE 9 (residues 1 to 680)
AUTHORS Apte,S.S., Seldin,M.F., Hayashi,M. and Olsen,B.R.
TITLE Cloning of the human and mouse type X collagen genes and mapping of
the mouse type X collagen gene to chromosome 10
JOURNAL Eur J Biochem 206 (1), 217-224 (1992)
PUBMED 1587271
REFERENCE 10 (residues 1 to 680)
AUTHORS Elima,K., Metsaranta,M., Kallio,J., Perala,M., Eerola,I.,
Garofalo,S., De Crombrugghe,B. and Vuorio,E.
TITLE Specific hybridization probes for mouse alpha 2(IX) and alpha 1(X)
collagen mRNAs
JOURNAL Biochim Biophys Acta 1130 (1), 78-80 (1992)
PUBMED 1543751
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
BY141606.1, CN664467.1, AC153960.3 and CJ326431.1.
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data to make the sequence consistent with the
reference genome assembly. The extent of this transcript is
supported by transcript alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AI663040.1, BY771794.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
SAMN00849374, SAMN00849383
[ECO:0000348]
##Evidence-Data-END##
##RefSeq-Attributes-START##
RefSeq Select criteria :: based on single protein-coding transcript
##RefSeq-Attributes-END##
FEATURES Location/Qualifiers
source 1..680
/organism="Mus musculus"
/strain="C57BL/6"
/db_xref="taxon:10090"
/chromosome="10"
/map="10 18.85 cM"
Protein 1..680
/product="collagen alpha-1(X) chain precursor"
/note="collagen alpha-1(X) chain; procollagen, type X,
alpha 1"
/calculated_mol_wt=64710
sig_peptide 1..18
/inference="COORDINATES: ab initio prediction:SignalP:6.0"
/calculated_mol_wt=2084
mat_peptide 19..680
/product="Collagen alpha-1(X) chain. /id=PRO_0000005771"
/note="propagated from UniProtKB/Swiss-Prot (Q05306.1)"
/calculated_mol_wt=64710
Region 19..56
/region_name="Nonhelical region (NC2)"
/note="propagated from UniProtKB/Swiss-Prot (Q05306.1)"
Region 54..531
/region_name="Disordered.
/evidence=ECO:0000256|SAM:MobiDB-lite"
/note="propagated from UniProtKB/Swiss-Prot (Q05306.1)"
Region 57..519
/region_name="Triple-helical region"
/note="propagated from UniProtKB/Swiss-Prot (Q05306.1)"
Region <279..>478
/region_name="gly_rich_SclB"
/note="LPXTG-anchored collagen-like adhesin Scl2/SclB;
NF038329"
/db_xref="CDD:468478"
Region 520..680
/region_name="Nonhelical region (NC1)"
/note="propagated from UniProtKB/Swiss-Prot (Q05306.1)"
Region 545..680
/region_name="C1Q"
/note="Complement component C1q domain; smart00110"
/db_xref="CDD:128420"
CDS 1..680
/gene="Col10a1"
/gene_synonym="Col10; Col10a-1"
/coded_by="NM_009925.4:79..2121"
/db_xref="CCDS:CCDS23780.1"
/db_xref="GeneID:12813"
/db_xref="MGI:MGI:88445"
ORIGIN
1 mlpqipflll mfltlvhgmf yaeryqtptg ikgplaspkt qyfipyaiks kgipvrgeqg
61 ipgppgptgp rghpgpsgpp gkpgygspgl qgepglpgpp gisatgkpgl pgppgkpger
121 gpyghkgdig paglpgprgp pgppgipgpa gisvpgkpgq qgltgapgpr gfpgekgaqg
181 apgvngrkge tgygspgrpg erglpgpqgp igppgpsgvg rrgengfpgq pgikgdrgfp
241 gemgpsgppg pqgppgkqgr egigkpgaig spgqpgipge kghpgapgia gppgapgfgk
301 qglpglrgqr gpaglpgapg akgergpagh pgepglpgsp gnmgpqgpkg ipgnhgipga
361 kgeiglvgpa gppgargarg ppgldgktgy pgepglngpk gnpglpgqkg dpgvggtpgl
421 rgpvgpvgak gvpghngeag prgepgipgt rgptgppgvp gfpgskgdpg npgapgpagi
481 atkglngptg ppgppgprgh sgepglpgpp gppgppgqav mpdgfikagq rprlsgmplv
541 sanhgvtgmp vsaftvilsk aypavgapip fdeilynrqq hydprsgift ckipgiyyfs
601 yhvhvkgthv wvglykngtp tmytydeysk gyldqasgsa imeltendqv wlqlpnaesn
661 glysseyvhs sfsgflvapm
//