NAD-dependent protein deacylase sirtuin-6 isoform 1 [Mus musculus]

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Sirt6 ablation in the liver causes fatty liver that increases cancer risky by upregulating Serpina12. [EMBO Rep. 2024]
Sirt6 ablation in the liver causes fatty liver that increases cancer risky by upregulating Serpina12.
Li L, Zeng J, Zhang X, Feng Y, Lei JH, Xu X, Chen Q, Deng CX. EMBO Rep. 2024 Mar; 25(3):1361-1386. Epub 2024 Feb 8.
Cardiac injury activates STING signaling via upregulating SIRT6 in macrophages after myocardial infarction. [Life Sci. 2024]
Cardiac injury activates STING signaling via upregulating SIRT6 in macrophages after myocardial infarction.
Kong W, Chen J, Ruan X, Xu X, Li X, Bao M, Shao Y, Bian X, Li R, Jiang Q, et al. Life Sci. 2024 Mar 15; 341:122474. Epub 2024 Feb 1.
Sirt6 enhances macrophage lipophagy and improves lipid metabolism disorder by regulating the Wnt1/β-catenin pathway in atherosclerosis. [Lipids Health Dis. 2023]
Sirt6 enhances macrophage lipophagy and improves lipid metabolism disorder by regulating the Wnt1/β-catenin pathway in atherosclerosis.
Wang T, Cheng Z, Zhao R, Cheng J, Ren H, Zhang P, Liu P, Hao Q, Zhang Q, Yu X, et al. Lipids Health Dis. 2023 Sep 22; 22(1):156. Epub 2023 Sep 22.

RefSeq mRNA
See reference mRNA sequence for the Sirt6 gene (NM_001378944.1).
RefSeq protein isoforms
See 5 reference sequence protein isoforms for the Sirt6 gene.

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Protein