Neuronal regeneration in C. elegans requires subcellular calcium release by ryanodine receptor channels and can be enhanced by optogenetic stimulation.
Sun L, Shay J, McLoed M, Roodhouse K, Chung SH, Clark CM, Pirri JK, Alkema MJ, Gabel CV. J Neurosci. 2014 Nov 26; 34(48):15947-56.