dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide - Protein

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PDE1 inhibition facilitates proteasomal degradation of misfolded proteins and protects against cardiac proteinopathy. [Sci Adv. 2019]
PDE1 inhibition facilitates proteasomal degradation of misfolded proteins and protects against cardiac proteinopathy.
Zhang H, Pan B, Wu P, Parajuli N, Rekhter MD, Goldberg AL, Wang X. Sci Adv. 2019 May; 5(5):eaaw5870. Epub 2019 May 22.
Generation and phenotypic characterization of Pde1a mutant mice. [PLoS One. 2017]
Generation and phenotypic characterization of Pde1a mutant mice.
Wang X, Yamada S, LaRiviere WB, Ye H, Bakeberg JL, Irazabal MV, Chebib FT, van Deursen J, Harris PC, Sussman CR, et al. PLoS One. 2017; 12(7):e0181087. Epub 2017 Jul 27.
Role of Ca2+/calmodulin-stimulated cyclic nucleotide phosphodiesterase 1 in mediating cardiomyocyte hypertrophy. [Circ Res. 2009]
Role of Ca2+/calmodulin-stimulated cyclic nucleotide phosphodiesterase 1 in mediating cardiomyocyte hypertrophy.
Miller CL, Oikawa M, Cai Y, Wojtovich AP, Nagel DJ, Xu X, Xu H, Florio V, Rybalkin SD, Beavo JA, et al. Circ Res. 2009 Nov 6; 105(10):956-64. Epub 2009 Sep 24.

RefSeq mRNA
See reference mRNA sequence for the Pde1a gene (NM_001355140.2).
RefSeq protein isoforms
See 12 reference sequence protein isoforms for the Pde1a gene.

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Protein