E3 SUMO-protein ligase NSE2 isoform 2 [Homo sapiens]

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View conserved domains detected in this protein sequence using CD-search.
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NSMCE2, a novel super-enhancer-regulated gene, is linked to poor prognosis and therapy resistance in breast cancer. [BMC Cancer. 2022]
NSMCE2, a novel super-enhancer-regulated gene, is linked to poor prognosis and therapy resistance in breast cancer.
Di Benedetto C, Oh J, Choudhery Z, Shi W, Valdes G, Betancur P. BMC Cancer. 2022 Oct 12; 22(1):1056. Epub 2022 Oct 12.
Rescue of collapsed replication forks is dependent on NSMCE2 to prevent mitotic DNA damage. [PLoS Genet. 2019]
Rescue of collapsed replication forks is dependent on NSMCE2 to prevent mitotic DNA damage.
Pond KW, de Renty C, Yagle MK, Ellis NA. PLoS Genet. 2019 Feb; 15(2):e1007942. Epub 2019 Feb 8.
Effects of Nephrolithiasis on Serum DNase (Deoxyribonuclease I and II) Activity and E3 SUMO-Protein Ligase NSE2 (NSMCE2) in Malaysian Individuals. [Biomed Environ Sci. 2015]
Effects of Nephrolithiasis on Serum DNase (Deoxyribonuclease I and II) Activity and E3 SUMO-Protein Ligase NSE2 (NSMCE2) in Malaysian Individuals.
Yusof F, Mehde AA, Mehdi WA, Raus RA, Ghazali H, Rahman AA. Biomed Environ Sci. 2015 Sep; 28(9):660-5.

RefSeq genomic sequence
See the genomic reference sequence for the NSMCE2 gene (NG_053069.1).
RefSeq mRNA
See reference mRNA sequence for the NSMCE2 gene (NM_001349487.2).
RefSeq protein isoforms
See 23 reference sequence protein isoforms for the NSMCE2 gene.

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Protein