exonuclease V [Homo sapiens]

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Functional deficiency of DNA repair gene EXO5 results in androgen-induced genomic instability and prostate tumorigenesis. [Oncogene. 2020]
Functional deficiency of DNA repair gene EXO5 results in androgen-induced genomic instability and prostate tumorigenesis.
Ali S, Zhang Y, Zhou M, Li H, Jin W, Zheng L, Yu X, Stark JM, Weitzel JN, Shen B. Oncogene. 2020 Feb; 39(6):1246-1259. Epub 2019 Oct 15.
Whole exome sequencing identifies PLEC, EXO5 and DNAH7 as novel susceptibility genes in testicular cancer. [Int J Cancer. 2018]
Whole exome sequencing identifies PLEC, EXO5 and DNAH7 as novel susceptibility genes in testicular cancer.
Paumard-Hernández B, Calvete O, Inglada Pérez L, Tejero H, Al-Shahrour F, Pita G, Barroso A, Carlos Triviño J, Urioste M, Valverde C, et al. Int J Cancer. 2018 Oct 15; 143(8):1954-1962. Epub 2018 Aug 9.
EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart. [Mol Cell. 2021]
EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart.
Hambarde S, Tsai CL, Pandita RK, Bacolla A, Maitra A, Charaka V, Hunt CR, Kumar R, Limbo O, Le Meur R, et al. Mol Cell. 2021 Jul 15; 81(14):2989-3006.e9. Epub 2021 Jun 30.

RefSeq mRNA
See reference mRNA sequence for the EXO5 gene (NM_001346951.2).
RefSeq protein isoforms
See 16 reference sequence protein isoforms for the EXO5 gene.

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Protein