LOCUS NP_001190468 391 aa linear PLN 20-OCT-2022
DEFINITION GroES-like zinc-binding dehydrogenase family protein [Arabidopsis
thaliana].
ACCESSION NP_001190468
VERSION NP_001190468.1
DBLINK BioProject: PRJNA116
BioSample: SAMN03081427
DBSOURCE REFSEQ: accession NM_001203539.1
KEYWORDS RefSeq.
SOURCE Arabidopsis thaliana (thale cress)
ORGANISM Arabidopsis thaliana
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae;
Pentapetalae; rosids; malvids; Brassicales; Brassicaceae;
Camelineae; Arabidopsis.
REFERENCE 1 (residues 1 to 391)
AUTHORS Tabata,S., Kaneko,T., Nakamura,Y., Kotani,H., Kato,T., Asamizu,E.,
Miyajima,N., Sasamoto,S., Kimura,T., Hosouchi,T., Kawashima,K.,
Kohara,M., Matsumoto,M., Matsuno,A., Muraki,A., Nakayama,S.,
Nakazaki,N., Naruo,K., Okumura,S., Shinpo,S., Takeuchi,C., Wada,T.,
Watanabe,A., Yamada,M., Yasuda,M., Sato,S., de la Bastide,M.,
Huang,E., Spiegel,L., Gnoj,L., O'Shaughnessy,A., Preston,R.,
Habermann,K., Murray,J., Johnson,D., Rohlfing,T., Nelson,J.,
Stoneking,T., Pepin,K., Spieth,J., Sekhon,M., Armstrong,J.,
Becker,M., Belter,E., Cordum,H., Cordes,M., Courtney,L.,
Courtney,W., Dante,M., Du,H., Edwards,J., Fryman,J., Haakensen,B.,
Lamar,E., Latreille,P., Leonard,S., Meyer,R., Mulvaney,E.,
Ozersky,P., Riley,A., Strowmatt,C., Wagner-McPherson,C., Wollam,A.,
Yoakum,M., Bell,M., Dedhia,N., Parnell,L., Shah,R., Rodriguez,M.,
See,L.H., Vil,D., Baker,J., Kirchoff,K., Toth,K., King,L.,
Bahret,A., Miller,B., Marra,M., Martienssen,R., McCombie,W.R.,
Wilson,R.K., Murphy,G., Bancroft,I., Volckaert,G., Wambutt,R.,
Dusterhoft,A., Stiekema,W., Pohl,T., Entian,K.D., Terryn,N.,
Hartley,N., Bent,E., Johnson,S., Langham,S.A., McCullagh,B.,
Robben,J., Grymonprez,B., Zimmermann,W., Ramsperger,U., Wedler,H.,
Balke,K., Wedler,E., Peters,S., van Staveren,M., Dirkse,W.,
Mooijman,P., Lankhorst,R.K., Weitzenegger,T., Bothe,G., Rose,M.,
Hauf,J., Berneiser,S., Hempel,S., Feldpausch,M., Lamberth,S.,
Villarroel,R., Gielen,J., Ardiles,W., Bents,O., Lemcke,K.,
Kolesov,G., Mayer,K., Rudd,S., Schoof,H., Schueller,C.,
Zaccaria,P., Mewes,H.W., Bevan,M. and Fransz,P.
CONSRTM Kazusa DNA Research Institute; Cold Spring Harbor and Washington
University in St Louis Sequencing Consortium; European Union
Arabidopsis Genome Sequencing Consortium
TITLE Sequence and analysis of chromosome 5 of the plant Arabidopsis
thaliana
JOURNAL Nature 408 (6814), 823-826 (2000)
PUBMED 11130714
REFERENCE 2 (residues 1 to 391)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (19-OCT-2022) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 3 (residues 1 to 391)
AUTHORS Krishnakumar,V., Cheng,C.-Y., Chan,A.P., Schobel,S., Kim,M.,
Ferlanti,E.S., Belyaeva,I., Rosen,B.D., Micklem,G., Miller,J.R.,
Vaughn,M. and Town,C.D.
TITLE Direct Submission
JOURNAL Submitted (17-MAY-2016) Plant Genomics, J. Craig Venter Institute,
9704 Medical Center Dr, Rockville, MD 20850, USA
REMARK Protein update by submitter
REFERENCE 4 (residues 1 to 391)
AUTHORS Swarbreck,D., Lamesch,P., Wilks,C. and Huala,E.
CONSRTM TAIR
TITLE Direct Submission
JOURNAL Submitted (18-FEB-2011) Department of Plant Biology, Carnegie
Institution, 260 Panama Street, Stanford, CA, USA
COMMENT REVIEWED REFSEQ: This record has been curated by TAIR and Araport.
The reference sequence is identical to AED95035.
Method: conceptual translation.
FEATURES Location/Qualifiers
source 1..391
/organism="Arabidopsis thaliana"
/db_xref="taxon:3702"
/chromosome="5"
/ecotype="Columbia"
Protein 1..391
/product="GroES-like zinc-binding dehydrogenase family
protein"
/calculated_mol_wt=41912
Region 8..388
/region_name="alcohol_DH_class_III"
/note="class III alcohol dehydrogenases; cd08300"
/db_xref="CDD:176260"
Site order(59,61,70..72,81,107..108,189,309,333)
/site_type="other"
/note="substrate binding site [chemical binding]"
/db_xref="CDD:176260"
Site order(59,81..82,189)
/site_type="other"
/note="catalytic Zn binding site [ion binding]"
/db_xref="CDD:176260"
Site order(60..61,189,193,214..218,238..239,243,283..284,
288..289,307..308,332..334,384)
/site_type="other"
/note="NAD binding site [chemical binding]"
/db_xref="CDD:176260"
Site order(111,114,117,125)
/site_type="other"
/note="structural Zn binding site [ion binding]"
/db_xref="CDD:176260"
Site order(115..116,119,121..122,124,126,274,279,290..291,
298..301,310,313..320,323..325,328..333)
/site_type="other"
/note="dimer interface [polypeptide binding]"
/db_xref="CDD:176260"
CDS 1..391
/gene="HOT5"
/locus_tag="AT5G43940"
/gene_synonym="ADH2; ALCOHOL DEHYDROGENASE 2; ATGSNOR1;
FALDH; GLUTATHIONE-DEPENDENT FORMALDEHYDE DEHYDROGENASE;
GSNOR; MRH10.4; MRH10_4; PAR2; PARAQUAT RESISTANT 2;
S-NITROSOGLUTATHIONE REDUCTASE; sensitive to hot
temperatures 5"
/coded_by="NM_001203539.1:110..1285"
/note="sensitive to hot temperatures 5 (HOT5); CONTAINS
InterPro DOMAIN/s: GroES-like (InterPro:IPR011032),
Alcohol dehydrogenase, zinc-containing, conserved site
(InterPro:IPR002328), Alcohol dehydrogenase GroES-like
(InterPro:IPR013154), Alcohol dehydrogenase, C-terminal
(InterPro:IPR013149), Alcohol dehydrogenase class
III/S-(hydroxymethyl)glutathione dehydrogenase
(InterPro:IPR014183), Alcohol dehydrogenase superfamily,
zinc-containing (InterPro:IPR002085); BEST Arabidopsis
thaliana protein match is: alcohol dehydrogenase 1
(TAIR:AT1G77120.1)."
/db_xref="GeneID:834417"
/db_xref="TAIR:AT5G43940"
/db_xref="Araport:AT5G43940"
ORIGIN
1 matqgqvitc kgtfildprt ltisavayep nkplviedvq vappqagevr ikilytalch
61 tdaytwsgkd peglfpcilg heaagivesv gegvtevqag dhvipcyqae creckfcksg
121 ktnlcgkvrs atgvgimmnd rksrfsvngk piyhfmgtst fsqytvvhdv svakidptap
181 ldkvcllgcg vptglgavwn takvepgsnv aifglgtvgl avaegaktag asriigidid
241 skkyetakkf gvnefvnpkd hdkpiqeviv dltdggvdys fecignvsvm raalecchkg
301 wgtsvivgva asgqeistrp fqlvtgrvwk gtafggfksr tqvpwlveky mnkeikvdey
361 ithnltlgei nkafdllheg tclrcvldts k
//