serine/threonine-protein phosphatase 6 catalytic subunit isoform c [Ho - Protein

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PP6 negatively modulates LUBAC-mediated M1-ubiquitination of RIPK1 and c-FLIP(L) to promote TNFα-mediated cell death. [Cell Death Dis. 2022]
PP6 negatively modulates LUBAC-mediated M1-ubiquitination of RIPK1 and c-FLIP(L) to promote TNFα-mediated cell death.
Wu G, Li D, Liang W, Sun W, Xie X, Tong Y, Shan B, Zhang M, Lu X, Yuan J, et al. Cell Death Dis. 2022 Sep 7; 13(9):773. Epub 2022 Sep 7.
Protein phosphatase 6 promotes neurite outgrowth by promoting mTORC2 activity in N2a cells. [J Biochem. 2021]
Protein phosphatase 6 promotes neurite outgrowth by promoting mTORC2 activity in N2a cells.
Kitamura N, Fujiwara N, Hayakawa K, Ohama T, Sato K. J Biochem. 2021 Sep 22; 170(1):131-138.
PPP6C negatively regulates oncogenic ERK signaling through dephosphorylation of MEK. [Cell Rep. 2021]
PPP6C negatively regulates oncogenic ERK signaling through dephosphorylation of MEK.
Cho E, Lou HJ, Kuruvilla L, Calderwood DA, Turk BE. Cell Rep. 2021 Mar 30; 34(13):108928.

RefSeq protein isoforms
See 11 reference sequence protein isoforms for the PPP6C gene.

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NP_001116841 [Domain Mapping of Disease Mut...]
NP_001116841
Domain Mapping of Disease Mutations
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OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
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