Mutations of RNF213 are responsible for sporadic cerebral cavernous malformation and lead to a mulberry-like cluster in zebrafish.
Lin J, Liang J, Wen J, Luo M, Li J, Sun X, Xu X, Li J, Wang D, Wang J, et al. J Cereb Blood Flow Metab. 2021 Jun; 41(6):1251-1263. Epub 2020 Apr 4.