DIS3-like exonuclease 2 isoform 1 [Rattus norvegicus]

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

Mammalian DIS3L2 exoribonuclease targets the uridylated precursors of let-7 miRNAs. [RNA. 2013]
Mammalian DIS3L2 exoribonuclease targets the uridylated precursors of let-7 miRNAs.
Ustianenko D, Hrossova D, Potesil D, Chalupnikova K, Hrazdilova K, Pachernik J, Cetkovska K, Uldrijan S, Zdrahal Z, Vanacova S. RNA. 2013 Dec; 19(12):1632-8. Epub 2013 Oct 18.
Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility. [Nat Genet. 2012]
Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility.
Astuti D, Morris MR, Cooper WN, Staals RH, Wake NC, Fews GA, Gill H, Gentle D, Shuib S, Ricketts CJ, et al. Nat Genet. 2012 Feb 5; 44(3):277-84. Epub 2012 Feb 5.
Mechanism of Dis3l2 substrate recognition in the Lin28-let-7 pathway. [Nature. 2014]
Mechanism of Dis3l2 substrate recognition in the Lin28-let-7 pathway.
Faehnle CR, Walleshauser J, Joshua-Tor L. Nature. 2014 Oct 9; 514(7521):252-256. Epub 2014 Aug 3.

RefSeq protein isoforms
See 7 reference sequence protein isoforms for the Dis3l2 gene.

BioProject
Proteins related to BioProjects
Nucleotide
Nucleotide sequence from coding region
PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Encoding mRNA
Link from protein to encoding mRNA
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Genome
Genome record encoding protein sequence
HomoloGene
Related HomoloGene
OMIM
OMIM records associated with protein sequence
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

Ensembl [Ensembl]
Ensembl
GlyGen glycoinformatics resource [GlyGen glycoinformatics resou...]
GlyGen glycoinformatics resource
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

Your browsing activity is empty.

Activity recording is turned off.

Protein