LOCUS NP_001076499 1080 aa linear VRT 16-SEP-2024
DEFINITION bromodomain-containing protein 1b [Danio rerio].
ACCESSION NP_001076499
VERSION NP_001076499.1
DBSOURCE REFSEQ: accession NM_001083030.1
KEYWORDS RefSeq.
SOURCE Danio rerio (zebrafish)
ORGANISM Danio rerio
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE 1 (residues 1 to 1080)
AUTHORS Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I,
Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y and
Bobe J.
TITLE Gene evolution and gene expression after whole genome duplication
in fish: the PhyloFish database
JOURNAL BMC Genomics 17, 368 (2016)
PUBMED 27189481
REMARK Publication Status: Online-Only
REFERENCE 2 (residues 1 to 1080)
AUTHORS Brocal I, White RJ, Dooley CM, Carruthers SN, Clark R, Hall A,
Busch-Nentwich EM, Stemple DL and Kettleborough RN.
TITLE Efficient identification of CRISPR/Cas9-induced
insertions/deletions by direct germline screening in zebrafish
JOURNAL BMC Genomics 17, 259 (2016)
PUBMED 27009152
REMARK Publication Status: Online-Only
REFERENCE 3 (residues 1 to 1080)
AUTHORS Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M,
Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD,
Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov
GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W and
Hertzano R.
TITLE RFX transcription factors are essential for hearing in mice
JOURNAL Nat Commun 6, 8549 (2015)
PUBMED 26469318
REMARK Publication Status: Online-Only
REFERENCE 4 (residues 1 to 1080)
AUTHORS Huang HT, Kathrein KL, Barton A, Gitlin Z, Huang YH, Ward TP,
Hofmann O, Dibiase A, Song A, Tyekucheva S, Hide W, Zhou Y and Zon
LI.
TITLE A network of epigenetic regulators guides developmental
haematopoiesis in vivo
JOURNAL Nat. Cell Biol. 15 (12), 1516-1525 (2013)
PUBMED 24240475
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence was derived from BC133132.1.
##Evidence-Data-START##
Transcript exon combination :: BC133132.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
SAMEA3505376, SAMEA3505378
[ECO:0000348]
##Evidence-Data-END##
FEATURES Location/Qualifiers
source 1..1080
/organism="Danio rerio"
/strain="AB"
/db_xref="taxon:7955"
/chromosome="25"
/map="25"
Protein 1..1080
/product="bromodomain-containing protein 1b"
/calculated_mol_wt=122136
Region 45..193
/region_name="EPL1"
/note="Enhancer of polycomb-like; pfam10513"
/db_xref="CDD:463128"
Region 142..>566
/region_name="COG5141"
/note="PHD zinc finger-containing protein [General
function prediction only]"
/db_xref="CDD:227470"
Region 559..656
/region_name="Bromo_brd1_like"
/note="Bromodomain; brd1_like subfamily. BRD1 is a
mammalian gene which encodes for a nuclear protein assumed
to be a transcriptional regulator. BRD1 has been
implicated with brain development and susceptibility to
schizophrenia and bipolar affective disorder; cd05512"
/db_xref="CDD:99944"
Site order(584,589,592,631,635,641)
/site_type="active"
/note="acetyllysine binding site [active]"
/db_xref="CDD:99944"
CDS 1..1080
/gene="brd1b"
/gene_synonym="zgc:158610"
/coded_by="NM_001083030.1:393..3635"
/db_xref="GeneID:100009661"
/db_xref="ZFIN:ZDB-GENE-070209-98"
ORIGIN
1 mrkkvrqnrv atpqrpsspi kpsrnrealt yaeaqrmvel eidgrvhrls iydkldvids
61 ddplaqeise ctsnkentek pqqvlvrsvr lknnqqkksa altnvqgspa qgrlpepkir
121 mveynlpavp rrpsvyytym ektldeldee veydmdeedy awlemmnekr ksdghsqvsq
181 nvfeflmdrf ekesffdsqa qgepqslide davccicmdg ecqnsnailf cdmcnlavhq
241 ecygvphipe grwlcrhcln spsqlaecif cpnkggalkr tdddrwghvv caiwvpevgf
301 tntlfiepid gvanipparw kltcylckkk gvgaciqcsk ancytafhvs caqkaglymk
361 mepvkevtes ggttfsvkkt ayccphtpng fvrrpltiyd dskskngvcq kaahrervkg
421 cqkkknkkpe sepdtvvptv sgpsitpksf ntilnqvsvq kkrmfvervl sywmlkrqsr
481 ngvplirrlq taiqtqkdpe ddpcvddhqt ltdqlkdlhr lrhdlerarl llelirkrek
541 lkreemklqq svlemqltpf piilrvaldq lqekdqakif aqpvsvtevp dyldhikhpm
601 dfstmrkrid gheyqsldef eedfnliinn clkynakdty fyragvrmrd hggvilrrtr
661 reterigfef psgihlpepp klelppsftw hdvdrvlnpa nrahmskdeq lkkllemldl
721 tfamkscpsr skrlkllkkt igdvrmdmgq kteppsleqn ntkeeekapl ilpqeeegdk
781 slppklepsd svpllknsds pcepptlkpm epspekcpkk vkfdgetfst sllnglspdv
841 lpsennvmva tstltepani vnrrtavlfr kskntspqkl lntsepsidc pqlgtktfls
901 vviprletll qhrkrthsas gdspdeedec pikrldtgls ngfsepkkgi ivtrpseprr
961 rcasessiss sgsgsiqens sdishtksgk gklamarrnt tddkkellnc tepgniskan
1021 klaadhrssv assgmpsqrr vhshpstgra pgrradavqv qgetlprpll rqqtqlamas
//