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bromodomain-containing protein 1b [Danio rerio]

NCBI Reference Sequence: NP_001076499.1

Identical Proteins FASTA Graphics 

LOCUS       NP_001076499            1080 aa            linear   VRT 16-SEP-2024
DEFINITION  bromodomain-containing protein 1b [Danio rerio].
ACCESSION   NP_001076499
VERSION     NP_001076499.1
DBSOURCE    REFSEQ: accession NM_001083030.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (residues 1 to 1080)
  AUTHORS   Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I,
            Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y and
            Bobe J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 1080)
  AUTHORS   Brocal I, White RJ, Dooley CM, Carruthers SN, Clark R, Hall A,
            Busch-Nentwich EM, Stemple DL and Kettleborough RN.
  TITLE     Efficient identification of CRISPR/Cas9-induced
            insertions/deletions by direct germline screening in zebrafish
  JOURNAL   BMC Genomics 17, 259 (2016)
   PUBMED   27009152
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 1080)
  AUTHORS   Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M,
            Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD,
            Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov
            GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W and
            Hertzano R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 1080)
  AUTHORS   Huang HT, Kathrein KL, Barton A, Gitlin Z, Huang YH, Ward TP,
            Hofmann O, Dibiase A, Song A, Tyekucheva S, Hide W, Zhou Y and Zon
            LI.
  TITLE     A network of epigenetic regulators guides developmental
            haematopoiesis in vivo
  JOURNAL   Nat. Cell Biol. 15 (12), 1516-1525 (2013)
   PUBMED   24240475
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC133132.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC133132.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA3505376, SAMEA3505378
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1080
                     /organism="Danio rerio"
                     /strain="AB"
                     /db_xref="taxon:7955"
                     /chromosome="25"
                     /map="25"
     Protein         1..1080
                     /product="bromodomain-containing protein 1b"
                     /calculated_mol_wt=122136
     Region          45..193
                     /region_name="EPL1"
                     /note="Enhancer of polycomb-like; pfam10513"
                     /db_xref="CDD:463128"
     Region          142..>566
                     /region_name="COG5141"
                     /note="PHD zinc finger-containing protein [General
                     function prediction only]"
                     /db_xref="CDD:227470"
     Region          559..656
                     /region_name="Bromo_brd1_like"
                     /note="Bromodomain; brd1_like subfamily. BRD1 is a
                     mammalian gene which encodes for a nuclear protein assumed
                     to be a transcriptional regulator. BRD1 has been
                     implicated with brain development and susceptibility to
                     schizophrenia and bipolar affective disorder; cd05512"
                     /db_xref="CDD:99944"
     Site            order(584,589,592,631,635,641)
                     /site_type="active"
                     /note="acetyllysine binding site [active]"
                     /db_xref="CDD:99944"
     CDS             1..1080
                     /gene="brd1b"
                     /gene_synonym="zgc:158610"
                     /coded_by="NM_001083030.1:393..3635"
                     /db_xref="GeneID:100009661"
                     /db_xref="ZFIN:ZDB-GENE-070209-98"
ORIGIN      
        1 mrkkvrqnrv atpqrpsspi kpsrnrealt yaeaqrmvel eidgrvhrls iydkldvids
       61 ddplaqeise ctsnkentek pqqvlvrsvr lknnqqkksa altnvqgspa qgrlpepkir
      121 mveynlpavp rrpsvyytym ektldeldee veydmdeedy awlemmnekr ksdghsqvsq
      181 nvfeflmdrf ekesffdsqa qgepqslide davccicmdg ecqnsnailf cdmcnlavhq
      241 ecygvphipe grwlcrhcln spsqlaecif cpnkggalkr tdddrwghvv caiwvpevgf
      301 tntlfiepid gvanipparw kltcylckkk gvgaciqcsk ancytafhvs caqkaglymk
      361 mepvkevtes ggttfsvkkt ayccphtpng fvrrpltiyd dskskngvcq kaahrervkg
      421 cqkkknkkpe sepdtvvptv sgpsitpksf ntilnqvsvq kkrmfvervl sywmlkrqsr
      481 ngvplirrlq taiqtqkdpe ddpcvddhqt ltdqlkdlhr lrhdlerarl llelirkrek
      541 lkreemklqq svlemqltpf piilrvaldq lqekdqakif aqpvsvtevp dyldhikhpm
      601 dfstmrkrid gheyqsldef eedfnliinn clkynakdty fyragvrmrd hggvilrrtr
      661 reterigfef psgihlpepp klelppsftw hdvdrvlnpa nrahmskdeq lkkllemldl
      721 tfamkscpsr skrlkllkkt igdvrmdmgq kteppsleqn ntkeeekapl ilpqeeegdk
      781 slppklepsd svpllknsds pcepptlkpm epspekcpkk vkfdgetfst sllnglspdv
      841 lpsennvmva tstltepani vnrrtavlfr kskntspqkl lntsepsidc pqlgtktfls
      901 vviprletll qhrkrthsas gdspdeedec pikrldtgls ngfsepkkgi ivtrpseprr
      961 rcasessiss sgsgsiqens sdishtksgk gklamarrnt tddkkellnc tepgniskan
     1021 klaadhrssv assgmpsqrr vhshpstgra pgrradavqv qgetlprpll rqqtqlamas
//
Feature
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Reference sequence information

  • RefSeq mRNA
    See reference mRNA sequence for the brd1b gene (NM_001083030.1).
  • RefSeq protein isoforms
    See the other reference sequence protein isoform for the brd1b gene (XP_005163199.1).

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