LOCUS NP_001000822 315 aa linear ROD 24-OCT-2024
DEFINITION olfactory receptor Olr860 [Rattus norvegicus].
ACCESSION NP_001000822
VERSION NP_001000822.1
DBSOURCE REFSEQ: accession NM_001000822.1
KEYWORDS RefSeq; RefSeq Select.
SOURCE Rattus norvegicus (Norway rat)
ORGANISM Rattus norvegicus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Rattus.
REFERENCE 1 (residues 1 to 315)
AUTHORS Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
TITLE Phylogenetic-based propagation of functional annotations within the
Gene Ontology consortium
JOURNAL Brief Bioinform 12 (5), 449-462 (2011)
PUBMED 21873635
REFERENCE 2 (residues 1 to 315)
AUTHORS Gibbs,R.A., Weinstock,G.M., Metzker,M.L., Muzny,D.M.,
Sodergren,E.J., Scherer,S., Scott,G., Steffen,D., Worley,K.C.,
Burch,P.E., Okwuonu,G., Hines,S., Lewis,L., DeRamo,C., Delgado,O.,
Dugan-Rocha,S., Miner,G., Morgan,M., Hawes,A., Gill,R., Celera,
Holt,R.A., Adams,M.D., Amanatides,P.G., Baden-Tillson,H.,
Barnstead,M., Chin,S., Evans,C.A., Ferriera,S., Fosler,C.,
Glodek,A., Gu,Z., Jennings,D., Kraft,C.L., Nguyen,T.,
Pfannkoch,C.M., Sitter,C., Sutton,G.G., Venter,J.C., Woodage,T.,
Smith,D., Lee,H.M., Gustafson,E., Cahill,P., Kana,A.,
Doucette-Stamm,L., Weinstock,K., Fechtel,K., Weiss,R.B., Dunn,D.M.,
Green,E.D., Blakesley,R.W., Bouffard,G.G., De Jong,P.J.,
Osoegawa,K., Zhu,B., Marra,M., Schein,J., Bosdet,I., Fjell,C.,
Jones,S., Krzywinski,M., Mathewson,C., Siddiqui,A., Wye,N.,
McPherson,J., Zhao,S., Fraser,C.M., Shetty,J., Shatsman,S.,
Geer,K., Chen,Y., Abramzon,S., Nierman,W.C., Havlak,P.H., Chen,R.,
Durbin,K.J., Simons,R., Ren,Y., Song,X.Z., Li,B., Liu,Y., Qin,X.,
Cawley,S., Worley,K.C., Cooney,A.J., D'Souza,L.M., Martin,K.,
Wu,J.Q., Gonzalez-Garay,M.L., Jackson,A.R., Kalafus,K.J.,
McLeod,M.P., Milosavljevic,A., Virk,D., Volkov,A., Wheeler,D.A.,
Zhang,Z., Bailey,J.A., Eichler,E.E., Tuzun,E., Birney,E.,
Mongin,E., Ureta-Vidal,A., Woodwark,C., Zdobnov,E., Bork,P.,
Suyama,M., Torrents,D., Alexandersson,M., Trask,B.J., Young,J.M.,
Huang,H., Wang,H., Xing,H., Daniels,S., Gietzen,D., Schmidt,J.,
Stevens,K., Vitt,U., Wingrove,J., Camara,F., Mar Alba,M.,
Abril,J.F., Guigo,R., Smit,A., Dubchak,I., Rubin,E.M., Couronne,O.,
Poliakov,A., Hubner,N., Ganten,D., Goesele,C., Hummel,O.,
Kreitler,T., Lee,Y.A., Monti,J., Schulz,H., Zimdahl,H.,
Himmelbauer,H., Lehrach,H., Jacob,H.J., Bromberg,S.,
Gullings-Handley,J., Jensen-Seaman,M.I., Kwitek,A.E., Lazar,J.,
Pasko,D., Tonellato,P.J., Twigger,S., Ponting,C.P., Duarte,J.M.,
Rice,S., Goodstadt,L., Beatson,S.A., Emes,R.D., Winter,E.E.,
Webber,C., Brandt,P., Nyakatura,G., Adetobi,M., Chiaromonte,F.,
Elnitski,L., Eswara,P., Hardison,R.C., Hou,M., Kolbe,D., Makova,K.,
Miller,W., Nekrutenko,A., Riemer,C., Schwartz,S., Taylor,J.,
Yang,S., Zhang,Y., Lindpaintner,K., Andrews,T.D., Caccamo,M.,
Clamp,M., Clarke,L., Curwen,V., Durbin,R., Eyras,E., Searle,S.M.,
Cooper,G.M., Batzoglou,S., Brudno,M., Sidow,A., Stone,E.A.,
Venter,J.C., Payseur,B.A., Bourque,G., Lopez-Otin,C., Puente,X.S.,
Chakrabarti,K., Chatterji,S., Dewey,C., Pachter,L., Bray,N.,
Yap,V.B., Caspi,A., Tesler,G., Pevzner,P.A., Haussler,D.,
Roskin,K.M., Baertsch,R., Clawson,H., Furey,T.S., Hinrichs,A.S.,
Karolchik,D., Kent,W.J., Rosenbloom,K.R., Trumbower,H.,
Weirauch,M., Cooper,D.N., Stenson,P.D., Ma,B., Brent,M.,
Arumugam,M., Shteynberg,D., Copley,R.R., Taylor,M.S., Riethman,H.,
Mudunuri,U., Peterson,J., Guyer,M., Felsenfeld,A., Old,S.,
Mockrin,S. and Collins,F.
CONSRTM Rat Genome Sequencing Project Consortium
TITLE Genome sequence of the Brown Norway rat yields insights into
mammalian evolution
JOURNAL Nature 428 (6982), 493-521 (2004)
PUBMED 15057822
COMMENT REVIEWED REFSEQ: This record has been curated by Janet Young and
Barbara Trask (FHCRC). The reference sequence was derived from
JAXUCZ010000005.1.
Summary: Olfactory receptors interact with odorant molecules in the
nose, to initiate a neuronal response that triggers the perception
of a smell. The olfactory receptor proteins are members of a large
family of G-protein-coupled receptors (GPCR) arising from single
coding-exon genes. Olfactory receptors share a 7-transmembrane
domain structure with many neurotransmitter and hormone receptors
and are responsible for the recognition and G protein-mediated
transduction of odorant signals. The olfactory receptor gene family
is the largest in the genome. [provided by RefSeq, Jul 2008].
Sequence Note: The RefSeq transcript and protein were derived from
genomic sequence to make the sequence consistent with the reference
genome assembly. The genomic coordinates used for the transcript
record were based on alignments.
##RefSeq-Attributes-START##
RefSeq Select criteria :: based on single protein-coding transcript
##RefSeq-Attributes-END##
FEATURES Location/Qualifiers
source 1..315
/organism="Rattus norvegicus"
/strain="BN"
/db_xref="taxon:10116"
/chromosome="5"
/map="5q36"
Protein 1..315
/product="olfactory receptor Olr860"
/note="olfactory receptor gene Olr860; olfactory receptor
2A2-like; olfactory receptor 860"
/calculated_mol_wt=35608
Region 28..297
/region_name="7tmA_OR1330-like"
/note="olfactory receptor 1330 and related proteins,
member of the class A family of seven-transmembrane G
protein-coupled receptors; cd15946"
/db_xref="CDD:320612"
Region 29..55
/region_name="TM helix 1"
/note="TM helix 1 [structural motif]"
/db_xref="CDD:320612"
Region 62..88
/region_name="TM helix 2"
/note="TM helix 2 [structural motif]"
/db_xref="CDD:320612"
Site order(84,87..88,100..105,107..108,111,156,158..162,198,
201..203,205..207,209..210,255,258..259,261..262,265,
271..272,274..276,279,282..283)
/site_type="other"
/note="putative ligand binding pocket [chemical binding]"
/db_xref="CDD:320612"
Region 100..130
/region_name="TM helix 3"
/note="TM helix 3 [structural motif]"
/db_xref="CDD:320612"
Region 143..164
/region_name="TM helix 4"
/note="TM helix 4 [structural motif]"
/db_xref="CDD:320612"
Region 198..228
/region_name="TM helix 5"
/note="TM helix 5 [structural motif]"
/db_xref="CDD:320612"
Region 235..265
/region_name="TM helix 6"
/note="TM helix 6 [structural motif]"
/db_xref="CDD:320612"
Region 272..297
/region_name="TM helix 7"
/note="TM helix 7 [structural motif]"
/db_xref="CDD:320612"
CDS 1..315
/gene="Or10ak14b"
/gene_synonym="Olr860"
/coded_by="NM_001000822.1:1..948"
/db_xref="GeneID:405111"
/db_xref="RGD:1333268"
ORIGIN
1 mwliplhnqs wvsefiligf srdpttnsil flvflliyls svlgngiivm lvcldtqlht
61 pmyfflctls lldmgyvttt mpqmlvhlla hsqtisfagc wlqmymfgtl gmtesilfiv
121 maydryvaic yplrytviln wsqciqlvsr tsacgfffsl lhtsftmslp ycgpnrvdhy
181 fcegpsvrsl acmdthliem vdlvlsvfvv ltpislivas yihiakailk ikstqgrcka
241 fstcashltv vtlfyapaic iymlpnssys peqdkqislf ynvftallnp vvyslrnrdl
301 kraflkvmgh vmvdq
//