membrane-bound transcription factor peptidase, site 2, isoform CRA_b, - Protein

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Mice heterozygous for an osteogenesis imperfecta-linked MBTPS2 variant display a compromised subchondral osteocyte lacunocanalicular network associated with abnormal articular cartilage. [Bone. 2023]
Mice heterozygous for an osteogenesis imperfecta-linked MBTPS2 variant display a compromised subchondral osteocyte lacunocanalicular network associated with abnormal articular cartilage.
Danyukova T, Alimy AR, Velho RV, Yorgan TA, Di Lorenzo G, von Kroge S, Tidow H, Wiegert JS, Hermans-Borgmeyer I, Schinke T, et al. Bone. 2023 Dec; 177:116927. Epub 2023 Oct 4.
MBTPS2 exacerbates albuminuria in streptozotocin-induced type I diabetic nephropathy by promoting endoplasmic reticulum stress-mediated renal damage. [Arch Physiol Biochem. 2022]
MBTPS2 exacerbates albuminuria in streptozotocin-induced type I diabetic nephropathy by promoting endoplasmic reticulum stress-mediated renal damage.
Liu Y, Xu D, Wang L, Du W, Zhang L, Xiang X. Arch Physiol Biochem. 2022 Aug; 128(4):1050-1057. Epub 2020 Apr 7.
p53-independent tumor suppression by cell-cycle arrest via CREB/ATF transcription factor OASIS. [Cell Rep. 2023]
p53-independent tumor suppression by cell-cycle arrest via CREB/ATF transcription factor OASIS.
Saito A, Kamikawa Y, Ito T, Matsuhisa K, Kaneko M, Okamoto T, Yoshimaru T, Matsushita Y, Katagiri T, Imaizumi K. Cell Rep. 2023 May 30; 42(5):112479. Epub 2023 May 12.

RefSeq protein
See the reference protein sequence for membrane-bound transcription factor site-2 protease (NP_758511.1).

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Protein