Tissue Inhibitor of Metalloproteinase 3 (TIMP3) mutations increase glycolytic activity and dysregulate glutamine metabolism in RPE cells.
Grenell A, Singh C, Raju M, Wolk A, Dalvi S, Jang GF, Crabb JS, Hershberger CE, Manian KV, Hernandez K, et al. Mol Metab. 2024 Oct; 88:101995. Epub 2024 Jul 22.