cytokine inducible SH2-containing protein, isoform CRA_d [Homo sapiens - Protein

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CIS deletion by CRISPR/Cas9 enhances human primary natural killer cell functions against allogeneic glioblastoma. [J Exp Clin Cancer Res. 2023]
CIS deletion by CRISPR/Cas9 enhances human primary natural killer cell functions against allogeneic glioblastoma.
Nakazawa T, Morimoto T, Maeoka R, Matsuda R, Nakamura M, Nishimura F, Ouji N, Yamada S, Nakagawa I, Park YS, et al. J Exp Clin Cancer Res. 2023 Aug 10; 42(1):205. Epub 2023 Aug 10.
CISH impairs lysosomal function in activated T cells resulting in mitochondrial DNA release and inflammaging. [Nat Aging. 2023]
CISH impairs lysosomal function in activated T cells resulting in mitochondrial DNA release and inflammaging.
Jin J, Mu Y, Zhang H, Sturmlechner I, Wang C, Jadhav RR, Xia Q, Weyand CM, Goronzy JJ. Nat Aging. 2023 May; 3(5):600-616. Epub 2023 Apr 17.
Genetic Predisposition to the Mortality in Septic Shock Patients: From GWAS to the Identification of a Regulatory Variant Modulating the Activity of a CISH Enhancer. [Int J Mol Sci. 2021]
Genetic Predisposition to the Mortality in Septic Shock Patients: From GWAS to the Identification of a Regulatory Variant Modulating the Activity of a CISH Enhancer.
Rosier F, Brisebarre A, Dupuis C, Baaklini S, Puthier D, Brun C, Pradel LC, Rihet P, Payen D. Int J Mol Sci. 2021 May 29; 22(11). Epub 2021 May 29.

RefSeq genomic sequence
See the genomic reference sequence for the CISH gene (NG_023194.1).

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