LOCUS AKI70761 455 aa linear SYN 01-JUN-2015
DEFINITION BLMH, partial [synthetic construct].
ACCESSION AKI70761
VERSION AKI70761.1
DBSOURCE accession KR710379.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (residues 1 to 455)
AUTHORS Sahni,N., Yi,S., Taipale,M., Fuxman Bass,J.I.,
Coulombe-Huntington,J., Yang,F., Peng,J., Weile,J., Karras,G.I.,
Wang,Y., Kovacs,I.A., Kamburov,A., Krykbaeva,I., Lam,M.H.,
Tucker,G., Khurana,V., Sharma,A., Liu,Y.Y., Yachie,N., Zhong,Q.,
Shen,Y., Palagi,A., San-Miguel,A., Fan,C., Balcha,D., Dricot,A.,
Jordan,D.M., Walsh,J.M., Shah,A.A., Yang,X., Stoyanova,A.K.,
Leighton,A., Calderwood,M.A., Jacob,Y., Cusick,M.E.,
Salehi-Ashtiani,K., Whitesell,L.J., Sunyaev,S., Berger,B.,
Barabasi,A.L., Charloteaux,B., Hill,D.E., Hao,T., Roth,F.P.,
Xia,Y., Walhout,A.J., Lindquist,S. and Vidal,M.
TITLE Widespread macromolecular interaction perturbations in human
genetic disorders
JOURNAL Cell 161 (3), 647-660 (2015)
PUBMED 25910212
REFERENCE 2 (residues 1 to 455)
AUTHORS Sahni,N., Yi,S., Taipale,M., Fuxman Bass,J.I.,
Coulombe-Huntington,J., Yang,F., Peng,J., Weile,J., Karras,G.I.,
Wang,Y., Kovacs,I.A., Kamburov,A., Krykbaeva,I., Lam,M.H.,
Tucker,G., Khurana,V., Sharma,A., Liu,Y.-Y., Yachie,N., Zhong,Q.,
Shen,Y., Palagi,A., San-Miguel,A., Fan,C., Balcha,D., Dricot,A.,
Jordan,D.M., Walsh,J.M., Shah,A.A., Yang,X., Stoyanova,A.K.,
Leighton,A., Calderwood,M.A., Jacob,Y., Cusick,M.E.,
Salehi-Ashtiani,K., Whitesell,L.J., Sunyaev,S., Berger,B.,
Barabasi,A.-L., Charloteaux,B., Hill,D.E., Hao,T., Roth,F.P.,
Xia,Y., Walhout,A.J.M., Lindquist,S. and Vidal,M.
TITLE Direct Submission
JOURNAL Submitted (14-MAY-2015) Center for Cancer Systems Biology (CCSB),
Department of Cancer Biology, Dana-Farber Cancer Institute, 450
Brookline Avenue, Boston, MA 02215, USA
COMMENT For distribution information, please check CCSB website
(http://ccsb.dfci.harvard.edu/ and
http://horfdb.dfci.harvard.edu/).
Method: conceptual translation.
FEATURES Location/Qualifiers
source 1..455
/organism="Homo sapiens"
/db_xref="taxon:9606"
Protein 1..>455
/product="BLMH"
Region 5..451
/region_name="Peptidase_C1_2"
/note="Peptidase C1-like family; pfam03051"
/db_xref="CDD:397262"
Site order(43,50,52..54,167..168,232,234,236,242,391)
/site_type="other"
/note="trimer interface [polypeptide binding]"
/db_xref="CDD:238328"
Site order(67,73,372,396)
/site_type="active"
/db_xref="CDD:238328"
Site 451
/site_type="active"
/note="G bulge [active]"
/db_xref="CDD:238328"
CDS 1..455
/gene="BLMH"
/coded_by="KR710379.1:66..>1430"
/note="full-length ORF without stop codon"
/transl_table=11
/db_xref="GeneID:642"
ORIGIN
1 msssglnsek vaaliqklns dpqfvlaqnv gtthdlldic lkratvqraq hvfqhavpqe
61 gkpitnqkss grcwifscln vmrlpfmkkl nieefefsqs ylffwdkver cyfflsafvd
121 taqrkepedg rlvqfllmnp andggqwdml vnivekygvi pkkcfpesyt teatrrmndi
181 lnhkmrefci rlrnlvhsga tkgeisatqd vmmeeifrvv ciclgnppet ftweyrdkdk
241 nyqkigpitp lefyrehvkp lfnmedkicl vndprpqhky nklytveyls nmvggrktly
301 nnqpidflkk mvaasikdge avwfgcdvgk hfnsklglsd mnlydhelvf gvslknmnka
361 erltfgeslm thamtftavs ekddqdgaft kwrvenswge dhghkgylcm tdewfseyvy
421 evvvdrkhvp eevlavleqe pivlpawdpm galae
//