REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma.
Di Marcotullio L, Ferretti E, De Smaele E, Argenti B, Mincione C, Zazzeroni F, Gallo R, Masuelli L, Napolitano M, Maroder M, et al. Proc Natl Acad Sci U S A. 2004 Jul 20; 101(29):10833-8. Epub 2004 Jul 12.