Hyaluronidase 3 (HYAL3) knockout mice do not display evidence of hyaluronan accumulation.
Atmuri V, Martin DC, Hemming R, Gutsol A, Byers S, Sahebjam S, Thliveris JA, Mort JS, Carmona E, Anderson JE, et al. Matrix Biol. 2008 Oct; 27(8):653-60. Epub 2008 Aug 14.