GTX [Homo sapiens]

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.

A homozygous missense variant in the homeobox domain of the NKX6-2 results in progressive spastic ataxia type 8 associated with lower limb weakness and neurological manifestations. [J Gene Med. 2020]
A homozygous missense variant in the homeobox domain of the NKX6-2 results in progressive spastic ataxia type 8 associated with lower limb weakness and neurological manifestations.
Almatrafi A, Umair M, Eldardear A, Al-Luqmani M, Hashmi JA, Albalawi AM, Alfadhel M, Ramzan K, Basit S. J Gene Med. 2020 Aug; 22(8):e3196. Epub 2020 Apr 16.
Expanding the clinical and neuroimaging features of NKX6-2-related hereditary spastic ataxia type 8. [Eur J Med Genet. 2020]
Expanding the clinical and neuroimaging features of NKX6-2-related hereditary spastic ataxia type 8.
Hosseini Bereshneh A, Hosseipour S, Rasoulinezhad MS, Pak N, Garshasbi M, Tavasoli AR. Eur J Med Genet. 2020 May; 63(5):103868. Epub 2020 Jan 28.
Genetic and phenotypic characterization of NKX6-2-related spastic ataxia and hypomyelination. [Eur J Neurol. 2020]
Genetic and phenotypic characterization of NKX6-2-related spastic ataxia and hypomyelination.
Chelban V, Alsagob M, Kloth K, Chirita-Emandi A, Vandrovcova J, Maroofian R, Davagnanam I, Bakhtiari S, AlSayed MD, Rahbeeni Z, et al. Eur J Neurol. 2020 Feb; 27(2):334-342. Epub 2019 Oct 17.

RefSeq protein isoforms
See 2 reference sequence protein isoforms for the NKX6-2 gene.

Nucleotide
Nucleotide sequence from coding region
PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Gene
Link to related Genes
OMIM
OMIM records associated with protein sequence
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

Your browsing activity is empty.

Activity recording is turned off.

Protein