Zeta-chain (TCR) associated protein kinase 70kDa [Homo sapiens]

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Decoding the deactivation mechanism of R192W mutation of ZAP-70 using molecular dynamics simulations and binding free energy calculations. [J Mol Model. 2023]
Decoding the deactivation mechanism of R192W mutation of ZAP-70 using molecular dynamics simulations and binding free energy calculations.
Zhang X, Liang W, Zheng G, Li B. J Mol Model. 2023 Nov 13; 29(12):371. Epub 2023 Nov 13.
Normal B cells express ZAP70 in chronic lymphocytic leukemia: A link between autoimmunity and lymphoproliferation? [Am J Hematol. 2024]
Normal B cells express ZAP70 in chronic lymphocytic leukemia: A link between autoimmunity and lymphoproliferation?
Ghergus D, Martin M, Knapp AM, Delmotte F, Joublin-Delavat A, Jung S, Schickel JN, Mendel I, Dupuis A, Drénou B, et al. Am J Hematol. 2024 Jan; 99(1):48-56. Epub 2023 Oct 19.
Combined immunodeficiency caused by pathogenic variants in the ZAP70 C-terminal SH2 domain. [Front Immunol. 2023]
Combined immunodeficiency caused by pathogenic variants in the ZAP70 C-terminal SH2 domain.
Mongellaz C, Vicente R, Noroski LM, Noraz N, Courgnaud V, Chinen J, Faria E, Zimmermann VS, Taylor N. Front Immunol. 2023; 14:1155883. Epub 2023 May 29.

RefSeq genomic sequence
See the genomic reference sequence for the ZAP70 gene (NG_007727.1).
RefSeq protein isoforms
See 16 reference sequence protein isoforms for the ZAP70 gene.

Nucleotide
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MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
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reagents [ExactAntigen/Labome]
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