PGE(2) inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function.
Morotti M, Grimm AJ, Hope HC, Arnaud M, Desbuisson M, Rayroux N, Barras D, Masid M, Murgues B, Chap BS, et al. Nature. 2024 May; 629(8011):426-434. Epub 2024 Apr 24.