RecName: Full=Caspase-2; Short=CASP-2; AltName: Full=Neural precursor - Protein

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Caspase-2 protects against ferroptotic cell death. [Cell Death Dis. 2024]
Caspase-2 protects against ferroptotic cell death.
Dawar S, Benitez MC, Lim Y, Dite TA, Yousef JM, Thio N, Garciaz S, Jackson TD, Milne JV, Dagley LF, et al. Cell Death Dis. 2024 Mar 1; 15(3):182. Epub 2024 Mar 1.
Bi-allelic truncating variants in CASP2 underlie a neurodevelopmental disorder with lissencephaly. [Eur J Hum Genet. 2024]
Bi-allelic truncating variants in CASP2 underlie a neurodevelopmental disorder with lissencephaly.
Uctepe E, Vona B, Esen FN, Sonmez FM, Smol T, Tümer S, Mancılar H, Geylan Durgun DE, Boute O, Moghbeli M, et al. Eur J Hum Genet. 2024 Jan; 32(1):52-60. Epub 2023 Oct 26.
Genuine selective caspase-2 inhibition with new irreversible small peptidomimetics. [Cell Death Dis. 2022]
Genuine selective caspase-2 inhibition with new irreversible small peptidomimetics.
Bosc E, Anastasie J, Soualmia F, Coric P, Kim JY, Wang LQ, Lacin G, Zhao K, Patel R, Duplus E, et al. Cell Death Dis. 2022 Nov 15; 13(11):959. Epub 2022 Nov 15.

RefSeq genomic sequence
See the genomic reference sequence for the CASP2 gene (NG_029248.1).
RefSeq protein isoforms
See 3 reference sequence protein isoforms for the CASP2 gene.

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P42575 [Domain Mapping of Disease Mut...]
P42575
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=Caspase-2; Short=CASP-2; AltName: Full=Neural precursor cell expre...
RecName: Full=Caspase-2; Short=CASP-2; AltName: Full=Neural precursor cell expressed developmentally down-regulated protein 2; Short=NEDD-2; AltName: Full=Protease ICH-1; Contains: RecName: Full=Caspase-2 subunit p18; Contains: RecName: Full=Caspase-2 subunit p13; Contains: RecName: Full=Caspase-2 subunit p12; Flags: Precursor
gi|83300977|sp|P42575.2|CASP2_HUMAN

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