RecName: Full=Protein phosphatase Mn(2+)-dependent 1K; AltName: Full=B - Protein

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PPM1K defects cause mild maple syrup urine disease: The second case in the literature. [Am J Med Genet A. 2023]
PPM1K defects cause mild maple syrup urine disease: The second case in the literature.
Ozcelik F, Arslan S, Ozguc Caliskan B, Kardas F, Ozkul Y, Dundar M. Am J Med Genet A. 2023 May; 191(5):1360-1365. Epub 2023 Jan 27.
The role of PP5 and PP2C in cardiac health and disease. [Cell Signal. 2021]
The role of PP5 and PP2C in cardiac health and disease.
Neumann J, Boknik P, Kirchhefer U, Gergs U. Cell Signal. 2021 Sep; 85:110035. Epub 2021 May 6.
Crystal structure and catalytic activity of the PPM1K N94K mutant. [J Neurochem. 2019]
Crystal structure and catalytic activity of the PPM1K N94K mutant.
Dolatabad MR, Guo LL, Xiao P, Zhu Z, He QT, Yang DX, Qu CX, Guo SC, Fu XL, Li RR, et al. J Neurochem. 2019 Feb; 148(4):550-560. Epub 2019 Jan 3.

RefSeq genomic sequence
See the genomic reference sequence for the PPM1K gene (NG_032931.1).
RefSeq protein isoforms
See 17 reference sequence protein isoforms for the PPM1K gene.

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Q8N3J5 [Domain Mapping of Disease Mut...]
Q8N3J5
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
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Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

RecName: Full=Protein phosphatase Mn(2+)-dependent 1K; AltName: Full=Branched-ch...
RecName: Full=Protein phosphatase Mn(2+)-dependent 1K; AltName: Full=Branched-chain alpha-ketoacid dehydrogenase phosphatase; Short=BCKDH; Short=BDP; AltName: Full=PP2C domain-containing protein phosphatase 1K; AltName: Full=PP2C-like mitochondrial protein; AltName: Full=PP2C-type mitochondrial phosphoprotein phosphatase; Short=PTMP; AltName: Full=Protein phosphatase 2C family member; AltName: Full=Protein phosphatase 2C isoform kappa; Short=PP2C-kappa; AltName: Full=[3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)]-phosphatase, mitochondrial; Flags: Precursor
gi|74750962|sp|Q8N3J5.1|PPM1K_HUMAN

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