RecName: Full=Syncytin-2; AltName: Full=Endogenous retrovirus group FR - Protein

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Transgenic expression of the HERV-W envelope protein leads to polarized glial cell populations and a neurodegenerative environment. [Proc Natl Acad Sci U S A. 2023]
Transgenic expression of the HERV-W envelope protein leads to polarized glial cell populations and a neurodegenerative environment.
Gruchot J, Lewen I, Dietrich M, Reiche L, Sindi M, Hecker C, Herrero F, Charvet B, Weber-Stadlbauer U, Hartung HP, et al. Proc Natl Acad Sci U S A. 2023 Sep 19; 120(38):e2308187120. Epub 2023 Sep 11.
HERV-W envelope expression in blood leukocytes as a marker of disease severity of COVID-19. [EBioMedicine. 2021]
HERV-W envelope expression in blood leukocytes as a marker of disease severity of COVID-19.
Garcia-Montojo M, Nath A. EBioMedicine. 2021 May; 67:103363. Epub 2021 May 13.
Endogenous retrovirus-encoded Syncytin-2 contributes to exosome-mediated immunosuppression of T cells†. [Biol Reprod. 2020]
Endogenous retrovirus-encoded Syncytin-2 contributes to exosome-mediated immunosuppression of T cells†.
Lokossou AG, Toudic C, Nguyen PT, Elisseeff X, Vargas A, Rassart É, Lafond J, Leduc L, Bourgault S, Gilbert C, et al. Biol Reprod. 2020 Feb 12; 102(1):185-198.

RefSeq protein
See the reference protein sequence for syncytin-2 preproprotein (NP_997465.1).

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P60508 [Domain Mapping of Disease Mut...]
P60508
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=Syncytin-2; AltName: Full=Endogenous retrovirus group FRD member 1...
RecName: Full=Syncytin-2; AltName: Full=Endogenous retrovirus group FRD member 1; AltName: Full=Envelope polyprotein; AltName: Full=HERV-FRD; AltName: Full=HERV-FRD_6p24.1 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor
gi|44887864|sp|P60508.1|SYCY2_HUMAN

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