RecName: Full=Integrin alpha-4; AltName: Full=CD49 antigen-like family - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...

Low CD49d expression in newly diagnosed chronic lymphocytic leukaemia may be associated with high-risk features and reduced treatment-free-intervals. [Eur J Haematol. 2022]
Low CD49d expression in newly diagnosed chronic lymphocytic leukaemia may be associated with high-risk features and reduced treatment-free-intervals.
Elizabeth S, Aidan K, David OB, Deirdre W, Sarah B, Emer A, Kanthi P, Crotty GM, Aileen W, Michelle C, et al. Eur J Haematol. 2022 Nov; 109(5):441-446. Epub 2022 Aug 9.
Integrin α4 up-regulation activates the hedgehog pathway to promote arsenic and benzo[α]pyrene co-exposure-induced cancer stem cell-like property and tumorigenesis. [Cancer Lett. 2020]
Integrin α4 up-regulation activates the hedgehog pathway to promote arsenic and benzo[α]pyrene co-exposure-induced cancer stem cell-like property and tumorigenesis.
Xie J, Yang P, Lin HP, Li Y, Clementino M, Fenske W, Yang C, Wang C, Wang Z. Cancer Lett. 2020 Nov 28; 493:143-155. Epub 2020 Aug 26.
CD49d promotes disease progression in chronic lymphocytic leukemia: new insights from CD49d bimodal expression. [Blood. 2020]
CD49d promotes disease progression in chronic lymphocytic leukemia: new insights from CD49d bimodal expression.
Tissino E, Pozzo F, Benedetti D, Caldana C, Bittolo T, Rossi FM, Bomben R, Nanni P, Chivilò H, Cattarossi I, et al. Blood. 2020 Apr 9; 135(15):1244-1254.

RefSeq genomic sequence
See the genomic reference sequence for the ITGA4 gene (NG_050623.2).
RefSeq protein isoforms
See 2 reference sequence protein isoforms for the ITGA4 gene.

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioAssay by Target (Summary)
BioAssay by Target (Summary)
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

P13612 [Domain Mapping of Disease Mut...]
P13612
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

RecName: Full=Integrin alpha-4; AltName: Full=CD49 antigen-like family member D;...
RecName: Full=Integrin alpha-4; AltName: Full=CD49 antigen-like family member D; AltName: Full=Integrin alpha-IV; AltName: Full=VLA-4 subunit alpha; AltName: CD_antigen=CD49d; Flags: Precursor
gi|311033436|sp|P13612.3|ITA4_HUMAN

Protein

Your browsing activity is empty.

Activity recording is turned off.

Protein