RecName: Full=Myocilin; AltName: Full=Myocilin 55 kDa subunit; AltName - Protein

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Variable phenotypic expression of MYOC mutations in a family with inherited pediatric glaucoma. [Can J Ophthalmol. 2023]
Variable phenotypic expression of MYOC mutations in a family with inherited pediatric glaucoma.
Mullie GA, Javidi S, Soucy JF, Lesk MR, Hamel P. Can J Ophthalmol. 2023 Dec; 58(6):e269-e270. Epub 2023 May 27.
Myocilin misfolding and glaucoma: A 20-year update. [Prog Retin Eye Res. 2023]
Myocilin misfolding and glaucoma: A 20-year update.
Saccuzzo EG, Youngblood HA, Lieberman RL. Prog Retin Eye Res. 2023 Jul; 95:101188. Epub 2023 May 20.
Human Pro370Leu Mutant Myocilin Induces the Phenotype of Open-Angle Glaucoma in Transgenic Mice. [Cell Mol Neurobiol. 2023]
Human Pro370Leu Mutant Myocilin Induces the Phenotype of Open-Angle Glaucoma in Transgenic Mice.
Cheng Y, Wu S, Yan X, Liu Q, Lin D, Zhang J, Wang N. Cell Mol Neurobiol. 2023 Jul; 43(5):2021-2033. Epub 2022 Sep 7.

RefSeq genomic sequence
See the genomic reference sequence for the MYOC gene (NG_008859.1).
RefSeq protein
See the reference protein sequence for myocilin precursor (NP_000252.1).

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Related Structures (List)
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Q99972 [Domain Mapping of Disease Mut...]
Q99972
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
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reagents
ExactAntigen/Labome

RecName: Full=Myocilin; AltName: Full=Myocilin 55 kDa subunit; AltName: Full=Tra...
RecName: Full=Myocilin; AltName: Full=Myocilin 55 kDa subunit; AltName: Full=Trabecular meshwork-induced glucocorticoid response protein; Contains: RecName: Full=Myocilin, N-terminal fragment; AltName: Full=Myocilin 20 kDa N-terminal fragment; Contains: RecName: Full=Myocilin, C-terminal fragment; AltName: Full=Myocilin 35 kDa N-terminal fragment; Flags: Precursor
gi|3024209|sp|Q99972.2|MYOC_HUMAN

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