RecName: Full=PAN2-PAN3 deadenylation complex catalytic subunit PAN2; - Protein

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Biallelic PAN2 variants in individuals with a syndromic neurodevelopmental disorder and multiple congenital anomalies. [Eur J Hum Genet. 2022]
Biallelic PAN2 variants in individuals with a syndromic neurodevelopmental disorder and multiple congenital anomalies.
Reuter MS, Zech M, Hempel M, Altmüller J, Heung T, Pölsler L, Santer R, Thiele H, Trost B, Kubisch C, et al. Eur J Hum Genet. 2022 May; 30(5):611-618. Epub 2022 Mar 18.
USP52 acts as a deubiquitinase and promotes histone chaperone ASF1A stabilization. [Nat Commun. 2018]
USP52 acts as a deubiquitinase and promotes histone chaperone ASF1A stabilization.
Yang S, Liu L, Cao C, Song N, Wang Y, Ma S, Zhang Q, Yu N, Ding X, Yang F, et al. Nat Commun. 2018 Mar 29; 9(1):1285. Epub 2018 Mar 29.
Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover. [Nat Struct Mol Biol. 2005]
Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover.
Yamashita A, Chang TC, Yamashita Y, Zhu W, Zhong Z, Chen CY, Shyu AB. Nat Struct Mol Biol. 2005 Dec; 12(12):1054-63. Epub 2005 Nov 13.

RefSeq protein isoforms
See 13 reference sequence protein isoforms for the PAN2 gene.

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Q504Q3 [Domain Mapping of Disease Mut...]
Q504Q3
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
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RecName: Full=PAN2-PAN3 deadenylation complex catalytic subunit PAN2; AltName: F...
RecName: Full=PAN2-PAN3 deadenylation complex catalytic subunit PAN2; AltName: Full=Inactive ubiquitin carboxyl-terminal hydrolase 52; AltName: Full=PAB1P-dependent poly(A)-specific ribonuclease; AltName: Full=Poly(A)-nuclease deadenylation complex subunit 2; Short=PAN deadenylation complex subunit 2
gi|296439280|sp|Q504Q3.3|PAN2_HUMAN

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