RecName: Full=Cytotoxic granule associated RNA binding protein TIA1; A - Protein

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The miR-30-5p/TIA-1 axis directs cellular senescence by regulating mitochondrial dynamics. [Cell Death Dis. 2024]
The miR-30-5p/TIA-1 axis directs cellular senescence by regulating mitochondrial dynamics.
Tak H, Cha S, Hong Y, Jung M, Ryu S, Han S, Jeong SM, Kim W, Lee EK. Cell Death Dis. 2024 Jun 10; 15(6):404. Epub 2024 Jun 10.
Mutagenesis and structural studies reveal the basis for the specific binding of SARS-CoV-2 SL3 RNA element with human TIA1 protein. [Nat Commun. 2023]
Mutagenesis and structural studies reveal the basis for the specific binding of SARS-CoV-2 SL3 RNA element with human TIA1 protein.
Zhang D, Qiao L, Lei X, Dong X, Tong Y, Wang J, Wang Z, Zhou R. Nat Commun. 2023 Jun 22; 14(1):3715. Epub 2023 Jun 22.
ALS mutations in the TIA-1 prion-like domain trigger highly condensed pathogenic structures. [Proc Natl Acad Sci U S A. 2022]
ALS mutations in the TIA-1 prion-like domain trigger highly condensed pathogenic structures.
Sekiyama N, Takaba K, Maki-Yonekura S, Akagi KI, Ohtani Y, Imamura K, Terakawa T, Yamashita K, Inaoka D, Yonekura K, et al. Proc Natl Acad Sci U S A. 2022 Sep 20; 119(38):e2122523119. Epub 2022 Sep 16.

RefSeq genomic sequence
See the genomic reference sequence for the TIA1 gene (NG_029967.1).
RefSeq protein isoforms
See 42 reference sequence protein isoforms for the TIA1 gene.

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P31483 [Domain Mapping of Disease Mut...]
P31483
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
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reagent reviews [ExactAntigen/Labome]
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ExactAntigen/Labome

RecName: Full=Cytotoxic granule associated RNA binding protein TIA1; AltName: Fu...
RecName: Full=Cytotoxic granule associated RNA binding protein TIA1; AltName: Full=Nucleolysin TIA-1 isoform p40; AltName: Full=RNA-binding protein TIA-1; AltName: Full=T-cell-restricted intracellular antigen-1; Short=TIA-1; AltName: Full=p40-TIA-1
gi|206729905|sp|P31483.3|TIA1_HUMAN

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